672906-71-7 Usage
Description
(S)-N-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE is a chiral aromatic amine compound with a trifluoromethyl and phenyl group in its structure. The (S)-enantiomer represents the left-handed version of the molecule, which is significant in the pharmaceutical and agrochemical industries due to its potential impact on the bioavailability, pharmacokinetics, and biological activity of the resulting compounds.
Uses
Used in Pharmaceutical Industry:
(S)-N-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE is used as a building block in organic synthesis for the development of new pharmaceutical compounds. Its trifluoromethyl group enhances the bioavailability and pharmacokinetics of the resulting drugs, while the phenyl group contributes to the molecule's aromaticity and chemical reactivity.
Used in Agrochemical Industry:
In the agrochemical field, (S)-N-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE serves as a key component in the synthesis of various agrochemical products. Its unique structure allows for the creation of molecules with specific biological activities, making it valuable for the development of effective and targeted agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 672906-71-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,2,9,0 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 672906-71:
(8*6)+(7*7)+(6*2)+(5*9)+(4*0)+(3*6)+(2*7)+(1*1)=187
187 % 10 = 7
So 672906-71-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H12F3N/c1-7(14-2)8-3-5-9(6-4-8)10(11,12)13/h3-7,14H,1-2H3/t7-/m0/s1
672906-71-7Relevant articles and documents
Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst
Salomó, Ernest,Gallen, Albert,Sciortino, Giuseppe,Ujaque, Gregori,Grabulosa, Arnald,Lledós, Agustí,Riera, Antoni,Verdaguer, Xavier
supporting information, p. 16967 - 16970 (2018/12/14)
A novel cationic [IrH(THF)(P,N)(imine)] [BArF] catalyst containing a P-stereogenic MaxPHOX ligand is described for the direct asymmetric hydrogenation of N-methyl and N-alkyl imines. This is the first catalytic system to attain high enantioselectivity (up to 94% ee) in this type of transformation. The labile tetrahydrofuran ligand allows for effective activation and reactivity, even at low temperatures. Density functional theory calculations allowed the rationalization of the stereochemical course of the reaction.
