672956-75-1 Usage
Description
2,6-BIS(2,2,2-TRIFLUOROACETYL)CYCLOHEXANONE is a chemical compound that serves as a key reactant in the synthesis of various nucleosides, specifically fluorinated pyrrolopyridine and pyrrolopyrimidine nucleosides. Its unique structure, featuring trifluoroacetyl groups attached to a cyclohexanone core, makes it a valuable intermediate in the development of pharmaceuticals and other specialty chemicals.
Uses
Used in Pharmaceutical Industry:
2,6-BIS(2,2,2-TRIFLUOROACETYL)CYCLOHEXANONE is used as a reactant in the synthesis of fluorinated pyrrolopyridine and pyrrolopyrimidine nucleosides for their potential applications in medicinal chemistry. These nucleosides may exhibit unique biological activities and therapeutic properties, making them valuable candidates for the development of new drugs and treatments.
Used in Chemical Research:
In the field of chemical research, 2,6-BIS(2,2,2-TRIFLUOROACETYL)CYCLOHEXANONE is utilized as a starting material or intermediate in the synthesis of complex organic molecules and compounds. Its reactivity and structural features allow for the exploration of new chemical reactions and the creation of novel molecules with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 672956-75-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,2,9,5 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 672956-75:
(8*6)+(7*7)+(6*2)+(5*9)+(4*5)+(3*6)+(2*7)+(1*5)=211
211 % 10 = 1
So 672956-75-1 is a valid CAS Registry Number.
672956-75-1Relevant articles and documents
2,4-Bridged 1,5-bis(fluoroalkyl)-1,3,5-triketones: Synthesis and properties
Chizhov,Pashkevich,R?schenthaler
, p. 267 - 272 (2003)
Symmetrical and unsymmetrical bis-fluoroacylcyclopentanones and cyclohexanones were synthesized. NMR data reveal that the keto-enol tautomeric equilibrium is changed markedly by the presence of a trimethylene bridge compared to an ethylene moiety. A considerable influence of the fluoroalkyl chain length was found for 2,6-(bisfluoroacyl)cyclohexanones.
Aromatization via a dibromination-double dehydrobromination sequence: A facile and convenient synthetic route to 2,6-bis(trifluoroacetyl)phenols
Sevenard, Dmitri V.,Kazakova, Olesya,Schoth, Ralf-Matthias,Lork, Enno,Chizhov, Dmitri L.,Poveleit, Joern,Roeschenthaler, Gerd-Volker
experimental part, p. 1867 - 1878 (2009/04/07)
An efficient and reliable method to synthesize 2,6-bis(trifluoroacetyl) phenols bearing various substituents in the 4-po-sition was developed. These valuable fluorinated building blocks were obtained from the corresponding cyclohexanones in a facile and convenient procedure, demonstrated to be superior to the traditional approaches. The application of this methodology to cyclohex-ane-1,4-dione opened access to 2,5-bis(polyfluoroacyl)-1,4- hydroquinones. Structural peculiarities of the obtained phenols as well as their 1,3-dicarbonyl or 1,3,5-tricarbonyl precursors are discussed on the basis of multinuclear NMR spectroscopy.
