67355-26-4

Basic information

• Product Name: 1,3-THIAZOLE-2,4-DIAMINE HYDROCHLORIDE
• Synonyms: 1,3-Thiazole-2,4-diaMine, HCl
• CAS NO: 67355-26-4
• Molecular Formula: C₃H₅N₃S
• Molecular Weight: 115.16
• Mol File: 67355-26-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-THIAZOLE-2,4-DIAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-THIAZOLE-2,4-DIAMINE HYDROCHLORIDE(67355-26-4)
• EPA Substance Registry System: 1,3-THIAZOLE-2,4-DIAMINE HYDROCHLORIDE(67355-26-4)

Safety Data

• Hazardous Substances Data: 67355-26-4(Hazardous Substances Data)

Usage

Uses

Thiazole-2,4-diamine is used as a reactant in the preparation of thiazoles as well as reactive modifications of thiazole moieties.

Upstream product

• 107-14-2 chloroacetonitrile 
• 17356-08-0 thiourea 

Downstream Products

• 804443-57-0 2-(2,4-diimino-thiazolidin-3-yl)-1-phenyl-ethanone 

Relevant articles and documents

Optimization of the manufacturing route to PF-610355 (1): Synthesis of intermediate 5

Tertiary carbinamine 5 is an isolated intermediate in the synthesis of a novel, inhaled β-2 adrenoreceptor agonist PF-610355. Process development for the key amide-formation and Ritter reactions, together with reaction understanding studies are discussed in context of the synthesis of 5. The optimized process employed to manufacture 140 kg of 5 is described, and was shown to have superior metrics to the preliminary commercial route.