674784-42-0

Basic information

• Product Name: 2-phenylthiazonaphthalic anhydride
• CAS NO: 674784-42-0
• Molecular Weight: 331.351
• Mol File: 674784-42-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-phenylthiazonaphthalic anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylthiazonaphthalic anhydride(674784-42-0)
• EPA Substance Registry System: 2-phenylthiazonaphthalic anhydride(674784-42-0)

Safety Data

• Hazardous Substances Data: 674784-42-0(Hazardous Substances Data)

Upstream product

• 52821-19-9 4-bromo-3-nitro-1,8-naphthalic anhydride 
• 100-52-7 benzaldehyde 
• 7704-34-9 sulfur 
• 852381-19-2 4-mercapto-3-amino-1,8-naphthalic anhydride 

Downstream Products

• 1097136-40-7 C₂₆H₂₃N₃O₂S 
• 1097136-44-1 C₂₆H₂₃N₃O₂S 
• 1097136-42-9 C₂₆H₂₃N₃O₂S 

Relevant articles and documents

Naphthalimide-thiazoles as novel photonucleases: Molecular design, synthesis, and evaluation

A new family of photonucleases, naphthalimide-thiazoles was synthesized and evaluated. These compounds intercalated into DNA efficiently and damaged DNA photochemically at concentrations as low as 5μM. Mechanistic experiment suggests that a novel naphthalimide-thiazole radical produced via an excited triple state might be involved in the DNA photodamage. Different activity may arise from the impact of substituents at 2-phenyl ring of thiazole on the electron population of excited triple state according to AM1 semi-empirical calculation.

Novel heterocyclic family of phenyl naphthothiazole carboxamides derived from naphthalimides: Synthesis, antitumor evaluation, and DNA photocleavage

A new heterocyclic family of (2-(dimethylamino)ethyl)-2-substituted phenylnaphtho[2,1-d]thiazole-5-carboxamides modified from naphthalimides was designed, synthesized, and quantitatively evaluated as antitumor agents and photonucleases. All these compound