675-67-2

Basic information

• Product Name: (2,2,2-trifluoroethoxy)acetic acid
• Synonyms: (2,2,2-trifluoroethoxy)acetic acid;2-(2,2,2-Trifluoroethoxy)acetic acid
• CAS NO: 675-67-2
• Molecular Formula: C₄H₅F₃O₃
• Molecular Weight: 158.08
• Mol File: 675-67-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 109-114 °C(Press: 24 Torr)
• Appearance: /
• Density: 1.412±0.06 g/cm3(Predicted)
• PKA: 3.08±0.10(Predicted)
• CAS DataBase Reference: (2,2,2-trifluoroethoxy)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2,2-trifluoroethoxy)acetic acid(675-67-2)
• EPA Substance Registry System: (2,2,2-trifluoroethoxy)acetic acid(675-67-2)

Safety Data

• Hazardous Substances Data: 675-67-2(Hazardous Substances Data)

Usage

Definition

ChEBI: An organofluorine compound consisting of acetic acid carrying a 2-(2,2,2-trifluoroethoxy) substituent.

Upstream product

• 75-89-8 2,2,2-trifluoroethanol 
• 3926-62-3 sodium monochloroacetic acid 
• 79-08-3 bromoacetic acid 
• 149605-53-8 methyl 2-(2,2,2-trifluoroethoxy)acetate 

Downstream Products

• 1426671-29-5 3-(4-methyl-3-nitrophenyl)-5-((2,2,2-trifluoroethoxy)methyl)-1,2,4-oxadiazole 
• 917806-79-2 C₂₅H₃₆F₃N₅O₂ 

Relevant articles and documents

TRIAZOLYLPIPERIDINE DERIVATIVES AND USE THEREOF IN THERAPY

The present invention provides compounds of formula (I) Wherein R1 , R2, R3 , R4 , Het and m are as defined in the description. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors.

Piperidine derivatives, compositions and use

Compounds of formula I, Ia or Ib and pharmaceutically acceptable salts thereof, useful in the treatment of neuropsychiatric disorders such as psychoses; pharmaceutical compositions comprising a compound of formula I and a pharmaceutically acceptable diluent or carrier; and methods of treating neuropschiatric disorders comprising administering to a mammal (including man) in need of such treatment an effective amount of a compound of formula I, or a pharmaceutically acceptable salt thereof; STR1