676495-94-6

Basic information

• Product Name: Piperidine, 3-(4-fluorophenyl)-
• Synonyms: Piperidine, 3-(4-fluorophenyl)-;3-(4-Fluorophenyl)piperidine
• CAS NO: 676495-94-6
• Molecular Formula: C₁₁H₁₄FN
• Molecular Weight: 179.23
• Mol File: 676495-94-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 262 ºC
• Flash Point: 112 ºC
• Appearance: /
• Density: 1.048
• Vapor Pressure: 0.0113mmHg at 25°C
• Refractive Index: 1.506
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: Piperidine, 3-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 3-(4-fluorophenyl)-(676495-94-6)
• EPA Substance Registry System: Piperidine, 3-(4-fluorophenyl)-(676495-94-6)

Safety Data

• Hazardous Substances Data: 676495-94-6(Hazardous Substances Data)

Usage

General Description

Piperidine, 3-(4-fluorophenyl)- is a chemical compound which belongs to a group of organic compounds called piperidines, recognized by the presence of a six-membered ring containing five carbon atoms and one nitrogen atom. The 4-fluorophenyl group indicates that a fluorine atom is attached to the fourth carbon atom in the phenyl ring, a structure consisting of six carbon atoms, known for its stability and aromatic nature. Information regarding this chemical’s usage or properties beyond its basic structure is limited and it might be of interest in the field of synthetic chemistry or pharmaceutical research. As with all chemicals, safe handling according to Material Safety Data Sheet (MSDS) instructions is crucial due to potential health risks.

InChI:InChI=1/C11H14FN/c12-11-5-3-9(4-6-11)10-2-1-7-13-8-10/h3-6,10,13H,1-2,7-8H2

Upstream product

• 85589-65-7 3-(4-fluorophenyl)pyridine 

Relevant articles and documents

Method for preparing piperidine compound by reducing pyridine compound through hydrogen transfer

The invention discloses a method for preparing a piperazine compound through a hydrogen transfer reduction of a pyridine compound, belonging to the field of organic synthesis. Under mild conditions, pyridine derivatives are used as raw materials, oxazolidine is used as a hydrogen transfer reagent, and cheap transition metals such as copper, cobalt, silver, palladium and the like are used as catalysts for catalysis of a hydrogen transfer reaction on 1,2,3,4-substitution sites, so a series of hydrogen transfer reduction product piperidine compounds are prepared, wherein the oxazaborolidine is obtained by a reaction of amino acid with a tetrahydrofuran complex of borane. The method has the advantages that product yield is high, reaction conditions are mild, the general applicability of raw materials is good, a hydrogen transfer reagent is cheap and easy to obtain, and good reproducibility can still be shown after quantitative reaction is conudcted. Therefore, the method of the invention provides an effective scheme for the industrial production of other high-value compounds containing the structure in the future.