676555-58-1

Basic information

• Product Name: 6-{2-[[(2-amino-6-benzyloxy-purin-9-yl)-acetyl]-(2-{2-[[(6-benzyloxycarbonylamino-purin-9-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-acetylamino}-ethyl)-amino]-acetylamino}-hexanoic acid tert-butyl ester
• Synonyms: 6-{2-[[(2-amino-6-benzyloxy-purin-9-yl)-acetyl]-(2-{2-[[(6-benzyloxycarbonylamino-purin-9-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-acetylamino}-ethyl)-amino]-acetylamino}-hexanoic acid tert-butyl ester
• CAS NO: 676555-58-1
• Molecular Weight: 1250.43
• Mol File: 676555-58-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-{2-[[(2-amino-6-benzyloxy-purin-9-yl)-acetyl]-(2-{2-[[(6-benzyloxycarbonylamino-purin-9-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-acetylamino}-ethyl)-amino]-acetylamino}-hexanoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-{2-[[(2-amino-6-benzyloxy-purin-9-yl)-acetyl]-(2-{2-[[(6-benzyloxycarbonylamino-purin-9-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-acetylamino}-ethyl)-amino]-acetylamino}-hexanoic acid tert-butyl ester(676555-58-1)
• EPA Substance Registry System: 6-{2-[[(2-amino-6-benzyloxy-purin-9-yl)-acetyl]-(2-{2-[[(6-benzyloxycarbonylamino-purin-9-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-acetylamino}-ethyl)-amino]-acetylamino}-hexanoic acid tert-butyl ester(676555-58-1)

Safety Data

• Hazardous Substances Data: 676555-58-1(Hazardous Substances Data)

Upstream product

• 149411-94-9 2-(2-amino-6-(benzyloxy)-9H-purin-9-yl)acetic acid 
• 676555-74-1 6-[2-(2-{2-[[(6-benzyloxycarbonylamino-purin-9-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-acetylamino}-ethylamino)-acetylamino]-hexanoic acid tert-butyl ester 
• 676555-56-9 6-{2-[allyloxycarbonyl-(2-{2-[[(6-benzyloxycarbonylamino-purin-9-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-acetylamino}-ethyl)-amino]-acetylamino}-hexanoic acid tert-butyl ester 
• 676555-52-5 [[2-(6-Benzyloxycarbonylamino-purin-9-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-acetic acid 
• 1027499-48-4 [[2-(6-Benzyloxycarbonylamino-purin-9-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-acetic acid methyl ester 
• 172405-21-9 methyl N-<2-((4-methoxyphenyl)-diphenylmethyl)aminoethyl> glycinate 
• 149376-67-0 [6-N-(benzyloxycarbonyl)-adenin-9-yl]-acetic acid 

Relevant articles and documents

Cyclic PNA-based compound directed against HIV-1 TAR RNA: Modelling, liquid-phase synthesis and TAR binding

A cyclic molecule including a hexameric PNA sequence has been designed and synthesized in order to target the TAR RNA loop of HIV-1 through the formation of a "kissing complex". For comparison, its linear analogue has also been investigated. The synthesis of the cyclic and linear PNA has been accomplished following a liquid-phase strategy using mixed PNA and fully N-protected (aminoethylglycinamide) fragments. The interactions of this cyclic PNA and its linear analogue with TAR RNA have been studied and the results indicate clearly that no interaction occurs between the cyclic antisense PNA and TAR RNA, whereas a tenuous interaction has been detected with its linear PNA analogue.