67684-64-4 Usage
Uses
rans-ACPD is a mGluR2 agonist.
Biological Activity
Equimolecular mixture of (1S,3R)- and (1R,3S)-ACPD. Selective agonist for metabotropic glutamate receptors; active at both group I and group II mGlu receptors (EC 50 values are 2, 15, 23 and ~800 μ M at mGluR 2 , mGluR 1 , mGluR 5 and mGluR 4 respectively).
Check Digit Verification of cas no
The CAS Registry Mumber 67684-64-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,6,8 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 67684-64:
(7*6)+(6*7)+(5*6)+(4*8)+(3*4)+(2*6)+(1*4)=174
174 % 10 = 4
So 67684-64-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7+/m0/s1
67684-64-4Relevant articles and documents
Carbamate-directed hydroboration: Enantioselective synthesis of the excitatory amino acid 1-aminocyclopentane-1,3-dicarboxylic acid
Hodgson, David M.,Thompson, Alison J.,Wadman, Sjoerd
, p. 3357 - 3358 (2007/10/03)
Carbamate-directed hydroboration (using BH3) of 1-substituted 3- cyclopentenes 2, 6 and 9 and an enantioselective synthesis of the excitatory amine acid 1-aminocyclopentane-1,3-dicarboxylic acid via carbamate-directed asymmetric hydroboration [90% de, 45% ee using (+)-IpcBH2] of cyclopentene 2 are described.