678-18-2

Basic information

• Product Name: 1H,1H,1H-NONAFLUORO-2-HEXANONE
• Synonyms: METHYL NONAFLUOROBUTYL KETONE;METHYL PERFLUORO-N-BUTYL KETONE;METHYL PERFLUOROBUTYL KETONE;1,1,1,2,2,3,3,4,4-NONAFLUORO-5-HEXANONE;1H,1H,1H-PERFLUORO-2-HEXANONE;1H,1H,1H-NONAFLUORO-2-HEXANONE;3,3,4,4,5,5,6,6,6-NONAFLUORO-2-HEXANONE;Perfluorohexanone
• CAS NO: 678-18-2
• Molecular Formula: C6H3F9O
• Molecular Weight: 262.07
• Product Categories: Fluorous Chemistry;Fluorous Compounds;Synthetic Organic Chemistry
• Mol File: 678-18-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 69°C
• Flash Point: 20.6 °C
• Appearance: /
• Density: 1,53 g/cm3
• Vapor Pressure: 77.2mmHg at 25°C
• Refractive Index: 1.286
• CAS DataBase Reference: 1H,1H,1H-NONAFLUORO-2-HEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1H,1H,1H-NONAFLUORO-2-HEXANONE(678-18-2)
• EPA Substance Registry System: 1H,1H,1H-NONAFLUORO-2-HEXANONE(678-18-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: UN 1224 3/PG II
• HazardClass: IRRITANT
• PackingGroup: II
• Hazardous Substances Data: 678-18-2(Hazardous Substances Data)

Usage

General Description

1H,1H,1H-Nonafluoro-2-hexanone is a fluorinated ketone compound that is commonly used as a solvent and reagent in various chemical reactions. It is a colorless liquid with a strong odor, and is highly volatile. This chemical is widely used in organic synthesis as a building block for the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is known for its high solvency power and low toxicity, making it a popular choice for industrial applications. Additionally, 1H,1H,1H-Nonafluoro-2-hexanone is also used as an intermediate in the manufacturing of fluorinated surfactants, which are used in products such as coatings, lubricants, and adhesives. Overall, this chemical compound plays a crucial role in the development and production of various important industrial and consumer goods.

InChI:InChI=1/C6H3F9O/c1-2(16)3(7,8)4(9,10)5(11,12)6(13,14)15/h1H3

Upstream product

• 125672-21-1 F-butyl-1 fluoro-2 ethanol 
• 144329-29-3 Toluene-4-sulfonic acid 2,2,3,3,4,4,5,5,5-nonafluoro-1-fluoromethyl-pentyl ester 

Relevant articles and documents

Reactivite des 1-F-alkyl-2-fluoroethyl p-toluenesulphonates en milieu basique

The simple 2-fluorotosylates eliminate p-toluenesulphonic acid (HOTs) in baisc media, the tosyl group being substituted by the action of a nucleophile.In contrast the F-alkylated homologous RF-CHOTs-CH2F undergo elimination of HF in the presence of a donor reagent leading to the 1-F-alkylvinyl p-toluenesulphonates RF-COTs=CH2.Depending on the reaction conditions and the nature of the base, these vinyl tosylates can react firther to give other F-alkylated products (F-alkylmethylketones, 1-hydroxy F-alkanes, 1-F-alkyl ethanols and F-alkylmethylhydrazones).