679-87-8

Basic information

• Product Name: 2,2,3,3-Tetrafluoropropyl iodide
• Synonyms: 2,2,3,3-TETRAFLUOROPROPYL IODIDE;2,2,3,3-TETRAFLUORO-1-IODOPROPANE;2,2,3,3-TETRAFLUOROIODOPROPANE;1H,1H,3H-TETRAFLUOROPROPYL IODIDE;1-IODO-2,2,3,3-TETRAFLUOROPROPANE;1,1,2,2-TETRAFLUORO-3-IODOPROPANE;3-IODO-1,1,2,2-TETRAFLUOROPROPANE;3-Iodo-1,1,2,2-tetrafluoropropane 98%
• CAS NO: 679-87-8
• Molecular Formula: C₃H₃F₄I
• Molecular Weight: 241.95
• Product Categories: Alkyl;Halogenated Hydrocarbons;Organic Building Blocks
• Mol File: 679-87-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 99 °C(lit.)
• Flash Point: 29.4 °C
• Appearance: /
• Density: 2.117 g/mL at 25 °C(lit.)
• Vapor Pressure: 44.2mmHg at 25°C
• Refractive Index: n20/D 1.414(lit.)
• CAS DataBase Reference: 2,2,3,3-Tetrafluoropropyl iodide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,3,3-Tetrafluoropropyl iodide(679-87-8)
• EPA Substance Registry System: 2,2,3,3-Tetrafluoropropyl iodide(679-87-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 679-87-8(Hazardous Substances Data)

Usage

General Description

2,2,3,3-Tetrafluoropropyl iodide is a chemical compound with the formula C3H5I. It is commonly used as a reagent in organic synthesis and as a building block for the preparation of various fluorinated compounds. 2,2,3,3-Tetrafluoropropyl iodide is a colorless liquid with a strong, irritating odor and is highly reactive. It is primarily used in the production of pharmaceuticals, agrochemicals, and materials for various industrial applications. Due to its highly reactive nature and potential health hazards, proper precautions should be taken when handling and using 2,2,3,3-Tetrafluoropropyl iodide in laboratory and industrial settings.

InChI:InChI=1/C3H3F4I/c4-2(5)3(6,7)1-8/h2H,1H2

Upstream product

• 2241-68-1 tris(2,2,3,3-tetrafluoropropyl)phosphite 
• 65675-12-9 1,1,3-trihydroperfluoropropyl benzenesulfonate 
• 786-31-2 p-toluenesulfonic acid-2,2,3,3-tetrafluoropropyl ester 

Downstream Products

• 133487-66-8 3-(2,2,3,3-tetrafluoropropoxy)benzaldehyde 
• 1132842-92-2 4-methyl-5-[(2,2,3,3-tetrafluoropropylthio)(2,3,6-trifluorophenyl)methyl]pyridine-2-carboxamide 
• 1132842-94-4 4-methyl-5-[(2,3,6-trifluorophenyl)methyl]pyridine-2-carboxamide 
• 444916-51-2 1-methyl-3-(2,2,3,3-tetrafluoropropoxy)benzene 
• 109230-72-0 4-(2,2,3,3-tetrafluoropropoxy)nitrobenzene 
• 40723-63-5 1,1,2,2-Tetrafluorpropan 

Relevant articles and documents

Highly stereoselective approach to 3-fluoroalkylated (E)-hex-3-ene-1,5- diyne derivatives via an addition-elimination reaction

Palladium(0)-catalyzed Sonogashira cross-coupling reaction of 2-fluoroalkylated (Z)-2-fluoro-1-iodoethene, which is easily prepared from commercially available polyfluorinated alcohols in facile three steps, with terminal alkynes in DMF at room temperature for 24 h took place stereospecifically to give the corresponding 1-fluoroalkylated (Z)-1-fluorobut-1-en-3-yne derivatives in good to excellent yield. Thus obtained fluoroalkylated 1-fluoroenynes were effectively subjected to addition-elimination reaction with various alkynyllithiums at room temperature, leading to 3-fluoroalkylated hex-3-ene-1,5-diyne derivatives in good to high yields with an excellent E selectivity.

α,α,ω-TRIHYDRO-α-HALOPERFLUOROALKANES

A synthesis has been developed for α,α,ω-trihydrohaloperfluoroalkanes, H(CF2CF2)n*CH2X, where X is Cl or Br and n is 1 or 4.It is based on the cleavage of the aromatic sulfonate esters of α,α,ω-trihydroperfluoroalkan-α-ols by alkali metal halides.