68005-30-1

Basic information

• Product Name: 2-broMobenzoxazole
• Synonyms: 2-broMobenzoxazole
• CAS NO: 68005-30-1
• Molecular Formula: C₇H₄BrNO
• Molecular Weight: 198.01676
• Mol File: 68005-30-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 263.8±23.0 °C(Predicted)
• Appearance: /
• Density: 1.710±0.06 g/cm3(Predicted)
• PKA: 0.62±0.10(Predicted)
• CAS DataBase Reference: 2-broMobenzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-broMobenzoxazole(68005-30-1)
• EPA Substance Registry System: 2-broMobenzoxazole(68005-30-1)

Safety Data

• Hazardous Substances Data: 68005-30-1(Hazardous Substances Data)

Upstream product

• 2382-96-9 benzo[d]oxazole-2-(3H)-thione 
• 273-53-0 benzoxazole 

Downstream Products

• 20934-81-0 4-(benzo[d]oxazol-2-yl)aniline 
• 833-50-1 2-phenylbenzo[d]oxazole 
• 2008-04-0 2-(trifluoromethyl)benzo[d]oxazole 
• 109243-80-3 benzo[d]oxazol-2-yl(phenyl)methanol 
• 1190280-72-8 C₁₈H₁₂F₃N₃O 

Relevant articles and documents

T -BuONa-mediated direct C-H halogenation of electron-deficient (hetero)arenes

An efficient halogenation of electron-deficient (hetero)arenes is described. The reaction utilizes common t-BuONa as a catalyst (for iodination) or a promoter (for bromination and chlorination), and perfluorobutyl iodide, CBr4 or CCl4 as the readily-available halogenating agents, respectively. The protocol features broad scope, high efficiency, mild conditions and gram scalability. An ionic pathway involving halogen bond formation and halophilic attack is proposed. The utility of the resulting iodinated heteroarenes is demonstrated in visible light-mediated Caryl-Caryl cross-coupling reaction.

AMINOISOXAZOLINE COMPOUNDS AS AGONISTS OF ALPHA7-NICOTINIC ACETYLCHOLINE RECEPTORS

The present invention relates to novel aminoisoxazoline compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of α7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.

A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives

A practical protocol for the one-pot synthesis of N-substituted 2-aminoazole derivatives is described, employing simple azole substrates, nitrogen nucleophiles, lithium tert-butoxide as the base, and iodine to mediate carbon-nitrogen bond formation. This method proceeds at room temperature under an air atmosphere using a normal benchtop set-up, or can be performed conveniently using microwave irradiation. Georg Thieme Verlag Stuttgart - New York.