68006-83-7 Usage
Chemical Properties
Off-White Solid
Uses
A pyrolysate of protein that exhibits potent mutagenic principles toward Salmonella typhimurium TA98 and TA100. 2-Amino-9H-pyrido[2,3-b]indole (AαC) and 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAαC) are two mutagenic and carcinogenic heterocyclic amines formed during ordinary cooking.
Safety Profile
Confirmed carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.
Check Digit Verification of cas no
The CAS Registry Mumber 68006-83-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,0,0 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 68006-83:
(7*6)+(6*8)+(5*0)+(4*0)+(3*6)+(2*8)+(1*3)=127
127 % 10 = 7
So 68006-83-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H11N3/c1-7-6-9-8-4-2-3-5-10(8)14-12(9)15-11(7)13/h2-6H,1H3,(H3,13,14,15)
68006-83-7Relevant articles and documents
Synthesis of Amino-Substituted α- And δ-Carbolines via Metal-Free [2 + 2 + 2] Cycloaddition of Functionalized Alkyne-Nitriles with Ynamides
Zhang, Jingyi,Guo, Meichao,Chen, Yajuan,Zhang, Shuangshuang,Wang, Xiao-Na,Chang, Junbiao
, p. 1331 - 1336 (2019/02/19)
A metal-free [2 + 2 + 2] cycloaddition of alkyne-cyanamides or ynamide-nitriles with ynamides is described for the efficient synthesis of amino-substituted α- and δ-carbolines. This novel methodology is environmentally friendly and allows for highly regioselective access to carboline derivatives in good to excellent yields with wide functional group tolerance.
Synthesis and mutagenic activity of alkyl derivatives of 2-amino-9H-pyrido[2,3-b]indole
Matsumoto,Yoshida,Tomita
, p. 2031 - 2035 (2007/10/02)
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