68386-85-6

Basic information

• Product Name: 2-cyano-5-oxo-3,5-diphenylpentanamide
• CAS NO: 68386-85-6
• Molecular Formula: C₁₈H₁₆N₂O₂
• Molecular Weight: 292.3318
• Mol File: 68386-85-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 588.2°C at 760 mmHg
• Flash Point: 309.5°C
• Density: 1.203g/cm³
• Vapor Pressure: 8.16E-14mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: 2-cyano-5-oxo-3,5-diphenylpentanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyano-5-oxo-3,5-diphenylpentanamide(68386-85-6)
• EPA Substance Registry System: 2-cyano-5-oxo-3,5-diphenylpentanamide(68386-85-6)

Safety Data

• Hazardous Substances Data: 68386-85-6(Hazardous Substances Data)

Upstream product

• 94-41-7 benzalacetophenone 
• 107-91-5 cyanoacetic acid amide 
• 67-56-1 methanol 
• 124-41-4 sodium methylate 
• 614-47-1 1,3-diphenyl-propen-3-one 

Downstream Products

• 57162-18-2 2-oxo-4,6-diphenyl-1,2,3,4-tetrahydropyridine-3-carboxamide 
• 5336-28-7 2-oxo-4,6-diphenyl-1,2,3,4-tetrahydropyridine-3-carbonitrile 
• 109012-83-1 dimethyl 2-(3-oxo-1,3-diphenylpropyl)malonate 
• 861351-98-6 5-bromo-2-hydroxy-4,6-diphenyl-nicotinonitrile 
• 861333-93-9 5-bromo-2-oxo-4,6-diphenyl-1,2,3,4-tetrahydro-pyridine-3-carbonitrile 
• 861351-94-2 3,5-dibromo-2-oxo-4,6-diphenyl-1,2,3,4-tetrahydro-pyridine-3-carbonitrile 
• 1373319-71-1 C₁₇H₁₃NS₂ 
• 1373319-69-7 C₂₃H₁₈N₂O 
• 576169-89-6 3,5-diphenyl-furan-2-carboxylic acid 
• 1373319-63-1 C₁₇H₁₃NO₂ 
• 16232-42-1 3-cyano-4,6-diphenyl-2-pyridone 
• 29261-44-7 2-(6-hydroxy-4-phenylpyridin-2-yl)phenyl 
• 16232-42-1 2-oxo-4,6-diphenyl-1,2-dihydropyridine-3-carbonitrile 
• 1354642-79-7 2,5-dioxo-3,5-diphenylpentanamide 

Relevant articles and documents

Facile regiocontrolled three-step synthesis of poly-substituted furans, pyrroles, and thiophenes: Consecutive michael addition of methyl cyanoacetate to α,β-enone, CuI-mediated aerobic oxidation, and acid-catalyzed paal-knorr synthesis

An efficient synthesis of poly-substituted furans, pyrroles, and thiophenes was carried out in a regiocontrolled manner via a three-step process; (i) conjugate addition of methyl cyanoacetate derivatives to α,β-enones, (ii) CuI-mediated aerobic oxidation,

Reactions of α,β-Unsaturated Ketones with Cyanoacetamide

3-Aryl-1-phenyl-2-propen-1-ones Ia-f and aroylphenylacetylenes Va-d reacted under reflux for 3 hours with cyanoacetamide in the presence of sodium ethoxide to give the corresponding 4-aryl-3-cyano-6-phenyl-2-(1H)pyridones VI.However, when ketones Ia-e wer