68555-67-9Relevant articles and documents
Studies on sulfinatodehalogenation. XXIX. The sulfinatodehalogenation of primary polyfluoroalkyl iodides and bromides by sodium disulfite
Fan-Hong, Wu,Bing-Nan, Huang
, p. 233 - 234 (1994)
Using DMF, acetonitrile and alcohols as cosolvents, both polyfluoroalkyl iodides, such as Cl(CF2)nI (n = 4, 6, 8; 1a-c) and F(CF2)nI (n = 6, 8; 1d, e), and polyfluoroalkyl bromides, such as Cl(CF2)6Br (3b) and F(CF2)8Br (3e), react with sodium disulfite in neutral aqueous solution to give the corresponding sulfinates Cl(CF2)nSO2Na (n = 4, 6, 8; 2a-c) and F(CF2)nSO2Na (n = 6, 8; 2d, e) in good yield.In a similar manner, CF3CCl3 (4a) reacted with sodium disulfite to give CF3CCl2SO2Na (5a).
Photoredox-Catalyzed Synthesis of Remote Fluoroalkylated Azaarene Derivatives and the α-Deuterated Analogues via 1, n-Hydrogen-Atom-Transfer-Involving Radical Reactions
Chen, Xiaowei,Wei, Wenhui,Li, Chunyang,Zhou, Hongwei,Qiao, Baokun,Jiang, Zhiyong
supporting information, p. 8744 - 8749 (2021/11/20)
A modular strategy to access the remote fluoroalkylated azaarene derivatives and the α-deuterated analogues, which are the isosteres of many pharmaceutically important compounds, is reported. Transformations under the sustainable photoredox catalysis platform could efficiently experience cascade radical addition, 1,n-hydrogen atom transfer (HAT), and single-electron reduction to offer the crucial anions α to azaarenes. Through reacting with H2O or the inexpensive D2O, two series of valuable products were obtained in high yields with substantial deuterium incorporation. The work demonstrates that the HAT of the α-sp3 C-H of the electron-withdrawing azaarenes with alkyl radicals is viable.
Method for preparing compound containing fluorine alkane
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Paragraph 0065; 0066, (2016/10/17)
The invention provides a method for preparing a compound containing fluorine alkane. According to the method, under the action of single electron oxidant, perfluoroalkyl sulfinate and 1-olefin react in first solvent, and the compound containing the fluorine alkane is obtained. The preparation method is mild in reaction condition and simple in synthesis path/route, scaled production is achieved easily, a high yield is achieved, and the compound containing the fluorine alkane has high purity.