687-28-5 Usage
Description
(2S)-2-ethylbutanedioic acid, also known as (S)-2-ethylsuccinic acid, is a chiral chemical compound with the molecular formula C6H10O4. It is a colorless, crystalline solid that serves as a building block in organic synthesis and is used in the production of pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
(2S)-2-ethylbutanedioic acid is used as an intermediate in the synthesis of various pharmaceuticals for its unique structure and properties.
Used in Agrochemical Industry:
(2S)-2-ethylbutanedioic acid is used as a building block in the production of agrochemicals to create effective and targeted products.
Used in Organic Synthesis:
(2S)-2-ethylbutanedioic acid is used as a chiral molecule in organic synthesis for its potential applications in the field of medicine and other industries.
It is important to handle (2S)-2-ethylbutanedioic acid with care, as it is potentially harmful if ingested or inhaled and can cause irritation to the skin and eyes.
Check Digit Verification of cas no
The CAS Registry Mumber 687-28-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,8 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 687-28:
(5*6)+(4*8)+(3*7)+(2*2)+(1*8)=95
95 % 10 = 5
So 687-28-5 is a valid CAS Registry Number.
687-28-5Relevant articles and documents
Diastereoselective conjugate addition of Grignard reagents to a homochiral fumaramide derived from Oppolzer's sultam
Reid, Gary P.,Brear, Kieron W.,Robins, David J.
, p. 793 - 801 (2007/10/03)
Conjugate addition of Grignard reagents to N,N′-fumaroylbis[(2R)- bornane-10,2-sultam] 1 occurred with moderate to high levels of diastereoselectivity. Diastereomeric excesses were estimated by analysis of the 1H NMR spectra of the succinamide mixtures and enantiomeric excesses from 19F NMR spectra of the bis Mosher esters of the diols produced by reductive cleavage of the succinamides. Saponification of the succinamides gave the corresponding (R)-succinic acids with ees up to 92% showing that addition of the Grignard reagents takes place selectively on the re-face of 1.
Asymmetric Synthesis of (R)- and (S)-4-(Substituted Benzyl)dihydrofuran-2(3H)-ones: An Application of the Ruthenium-binap Complex-catalysed Asymmetric Hydrogenation of Alkylidenesuccinic Acids
Shao, Liming,Miyata, Shiro,Muramatsu, Hitoshi,Kawano, Hiroyuki,Ishii, Youichi,et al.
, p. 1441 - 1445 (2007/10/02)
A concise synthesis of (S)- or (R)-4-(substituted benzyl)dihydrofuran-2(3H)-ones (1) with high enantiomeric purity is presented. (S)- or (R)-(Substituted benzyl)succinic acids (6) 97percent enantiomeric excess) were first prepared by Ru2Cl4(R)- or (S
