68809-65-4

Basic information

• Product Name: ethyl 1,4-dimethyl-1H-pyrazole-3-carboxylate
• Synonyms: ethyl 1,4-dimethyl-1H-pyrazole-3-carboxylate;Ethyl 1,4-diMethylpyrazole-3-carboxylate;1H-Pyrazole-3-carboxylic acid, 1,4-diMethyl-, ethyl ester;1,4-Dimethyl-1H-pyrazol-3-carboxylic acid ethyl ester
• CAS NO: 68809-65-4
• Molecular Formula: C₈H₁₂N₂O₂
• Molecular Weight: 168.19308
• Mol File: 68809-65-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 248℃
• Flash Point: 104℃
• Appearance: /
• Density: 1.12
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ethyl 1,4-dimethyl-1H-pyrazole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1,4-dimethyl-1H-pyrazole-3-carboxylate(68809-65-4)
• EPA Substance Registry System: ethyl 1,4-dimethyl-1H-pyrazole-3-carboxylate(68809-65-4)

Safety Data

• Hazardous Substances Data: 68809-65-4(Hazardous Substances Data)

Usage

General Description

Ethyl 1,4-dimethyl-1H-pyrazole-3-carboxylate is a chemical compound with the molecular formula C8H12N2O2. It is classified under the category of pyrazoles, which are a type of organic compound with a five-membered aromatic ring, containing two nitrogen atoms with nonadjacent positions. Known for its chemical stability, this compound is generally utilized in chemical synthesis and pharmaceutical applications. Its synthesis often involves the use of ethyl chloroformate associated with 1,4-dimethylpyrazole. It's also important to note the potential risks and safety measures required when handling this chemical substance due to its potentially hazardous characteristics.

Upstream product

• 64-17-5 ethanol 
• 7339-53-9 methyl hydrazine hydrochloride 
• 121781-57-5 (E)-1,1,1-trichloro-4-ethoxy-3-methylbut-3-en-2-one 
• 594-27-4 tetramethylstannane 
• 6076-12-6 ethyl 4-methyl-1H-pyrazole-5-carboxylate 
• 74-88-4 methyl iodide 

Downstream Products

• 1616930-75-6 C₁₈H₂₂N₂O₃ 
• 1616931-07-7 C₁₅H₁₇ClN₂O₃ 
• 89202-86-8 N-Phenyl-1,4-dimethylpyrazole-3-carboxamide 

Relevant articles and documents

AMIDO COMPOUNDS AS AhR MODULATORS

Provided herein are compounds, compositions and methods of using the compounds and compositions for the treatment of diseases modulated, as least in part, by AhR. The compounds are represented by formulae Formula (I), (II), (III), (iv): wherein the letters and symbols a, b, c, d, e, f, g, Z, R1b, R2a and R2b have the meanings provided in the specification.

Haloacetylated enol ethers. 11 [16]. Synthesis of 1-methyl- and 1- phenyl pyrazole-3(5)-ethyl esters. A one-pot procedure

A one-pot synthesis of 1-methyl- and 1-phenylpyrazole-3(5)-ethyl esters 2,3a-e by the cyclocondensation of β-alkoxyvinyl trichloromethyl ketones 1a- e with methyl and phenyl hydrazine hydrochloride under mild conditions, is reported. A study using compounds la-e with different substituents proved that these are versatile building blocks for the synthesis of pyrazole derivatives, having a 3(5)-ethoxycarbonyl substituent in good yields (60- 89%). The hydrazine and β-alkoxyvinyl trichloromethyl ketone substituent effects on the reaction regiochemistry on the formation of the 1,3- and 1,5- isomer were observed.