68836-61-3Relevant articles and documents
Synthetic method for triflumizole metabolite FM-6-1
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, (2019/04/10)
The invention relates to a synthetic method for a triflumizole metabolite FM-6-1, and belongs to the field of pesticide synthesis. The synthetic method has the advantages that the process design is reasonable, the raw materials are cheap in price, and the purity of an obtained product is high. The synthetic method takes 2-amino-5-chlorobenzotrifluoride (II) as a raw material and mainly comprises the following steps that 1) the compound (II) and a compound (III) are subjected to acylation reaction so as to obtain a compound (VI); 2) the compound (VI) is subjected to chlorination through chloride agents so as to obtain a compound(V); and 3) the compound (V) is treated through ammonia so as to obtain a compound (I). The triflumizole metabolite FM-6-1 prepared through the synthetic method hasthe advantages that the chemical purity can reach 99% or above, the total yield can reach about 90%, a high-quality standard substance can be provided for the agricultural residue detection industry,and important social application values are achieved.