689291-89-2

Basic information

• Product Name: 5-BROMO-2-IODOBENZALDEHYDE
• Synonyms: 5-BROMO-2-IODOBENZALDEHYDE
• CAS NO: 689291-89-2
• Molecular Formula: C₇H₄BrIO
• Molecular Weight: 310.91
• Mol File: 689291-89-2.mol
• Article Data: 17

Chemical Properties

• Melting Point: 89-90 ºC
• Boiling Point: 312.152°C at 760 mmHg
• Flash Point: 142.585°C
• Appearance: /
• Density: 2.231
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.696
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 5-BROMO-2-IODOBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-IODOBENZALDEHYDE(689291-89-2)
• EPA Substance Registry System: 5-BROMO-2-IODOBENZALDEHYDE(689291-89-2)

Safety Data

• Hazardous Substances Data: 689291-89-2(Hazardous Substances Data)

Usage

Uses

5-Bromo-2-iodobenzaldehyde is a useful synthetic intermediate. It is used to prepare aza-fused polycyclic quinolines via copper-catalyzed cascade intermolecular condensation. It is also used in the synthesis of oxoindenopyrroles via copper-catalyzed tandem cycloaddition and coupling of iodoarylynones with isocyanides.

InChI:InChI=1/C7H4BrIO/c8-6-1-2-7(9)5(3-6)4-10/h1-4H

Upstream product

• 199786-58-8 (5-bromo-2-iodo-phenyl)-methanol 
• 181765-86-6 5-bromo-2-iodo-benzoic acid methyl ester 
• 21740-00-1 5-bromo-2-iodo-benzoic acid 
• 118-92-3 anthranilic acid 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 116632-39-4 2-methyl-4-bromoiodobenzene 
• 450412-27-8 4-bromo-1-iodobenzoic acid ethyl ester 
• 88-67-5 2-Iodobenzoic acid 
• 610-97-9 o-iodo-methyl-benzoic acid 

Downstream Products

• 1038395-08-2 1,4-bis(5-bromo-2-iodostyryl)benzene 
• 1038395-11-7 5-bromo-2-((triisopropylsilyl)ethynyl)benzaldehyde 
• 1175525-90-2 (5-Bromo-2-iodo-benzyl)-ethyl-amine 
• 1222168-93-5 4-bromo-2-(diethoxymethyl)-1-iodobenzene 
• 1038395-09-3 C₄₂H₅₀Si₄ 
• 1038395-10-6 C₃₀H₁₈ 
• 1038395-15-1 C₆₂H₄₂O₈ 
• 1263055-18-0 2,5-diethynylbenzaldehyde 
• 1263055-20-4 C₂₇H₁₈O₅ 
• 1263055-24-8 2-((triisopropylsilyl)ethynyl)-5-((trimethylsilyl)ethynyl)benzaldehyde 
• 1263055-26-0 5-ethynyl-2-((triisopropylsilyl)ethynyl)benzaldehyde 
• 1263055-28-2 methyl 2-((3-formyl-4-((triisopropylsilyl)ethynyl)phenyl)ethynyl)benzoate 
• 1263055-30-6 methyl 2-((4-ethynyl-3-formylphenyl)ethynyl)benzoate 
• 1263055-32-8 C₂₇H₂₁NO₃ 

Relevant articles and documents

INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE - SYNTHESIS AND USE THEREOF FOR TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND LYMPHOMA

The present invention relates to new compounds of general formula I, their synthesis, their pharmaceutically acceptable salts, and their use in treatment of T-cell acute lymphoblastic leukemia and lymphoma.

Iodolopyrazolium Salts: Synthesis, Derivatizations, and Applications

The synthesis of iodolopyrazolium triflates via an oxidative cyclization of 3-(2-iodophenyl)-1H-pyrazoles is described. The reaction is characterized by a broad substrate scope, and various applications of these novel cyclic iodolium salts acting as useful synthetic intermediates are demonstrated, in particular in site-selective ring openings. This was finally applied to generate derivatives of the anti-inflammatory drug celecoxib. Their application as highly active halogen-bond donors is shown as well.

Cu-Catalyzed Enantioselective Ring Opening of Cyclic Diaryliodoniums toward the Synthesis of Chiral Diarylmethanes

A Cu-catalyzed enantioselective desymmetrizing ring-opening reaction of six-membered cyclic diaryliodonium salts with carboxylic acids or thioacids is reported for the facile access to chiral diarylmethanes. A Cu/[cyclopropyl bis(oxazoline)] catalyst well