69222-61-3

Basic information

• Product Name: 2H-Cyclopenta[b]furan-2-one, hexahydro-4-(hydroxymethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3aR,4S,5R,6aS)-
• Synonyms: 2H-Cyclopenta[b]furan-2-one, hexahydro-4-(hydroxymethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3aR,4S,5R,6aS)-;Corey lactone THP;(3aR,4S,5R,6aS)-Hexahydro-4-(hydroxymethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-cyclopenta[b]furan-2-one;Corey lactone;2H-Cyclopenta[b]furan-2-one, hexahydro-4-(hydroxymethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3aR,4S,5R,6aS)- (9CI);(3aR,4S,5R,6aS)-4-(hydroxymethyl)-5-(tetrahydro-2H-pyran-2-yloxy)hexahydro-2H-cyclopenta[b]furan-2-one;2H-Cyclopenta[b]furan-2-one;hexahydro-4-(hydroxyMethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-
• CAS NO: 69222-61-3
• Molecular Formula: C₁₃H₂₀O₅
• Molecular Weight: 256.29
• Product Categories: API intermediates
• Mol File: 69222-61-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 454.2±45.0 °C(Predicted)
• Appearance: Colorless or light yellow viscous liquid
• Density: 1.26
• Refractive Index: 1.531
• Storage Temp.: 2-8°C
• PKA: 14.79±0.10(Predicted)
• CAS DataBase Reference: 2H-Cyclopenta[b]furan-2-one, hexahydro-4-(hydroxymethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3aR,4S,5R,6aS)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Cyclopenta[b]furan-2-one, hexahydro-4-(hydroxymethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3aR,4S,5R,6aS)-(69222-61-3)
• EPA Substance Registry System: 2H-Cyclopenta[b]furan-2-one, hexahydro-4-(hydroxymethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3aR,4S,5R,6aS)-(69222-61-3)

Safety Data

• Hazardous Substances Data: 69222-61-3(Hazardous Substances Data)

Usage

Uses

(3aR,4S,5R,6aS)-hexahydro-4-(hydroxymethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-Cyclopenta[b]furan-2-one belongs to furan heterocyclic derivatives and can be used as pharmaceutical intermediates in medical experimental research.

InChI:InChI=1/C13H20O5/c14-7-9-8-5-12(15)17-10(8)6-11(9)18-13-3-1-2-4-16-13/h8-11,13-14H,1-7H2/t8-,9-,10+,11-,13?/m1/s1

Upstream product

• 32233-40-2 (3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one 
• 58707-50-9 (3aR,4S,5R,6aS)-4-((tert-butyldimethylsilyloxy)methyl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one 
• 65025-95-8 (3aR,4S,5R,6aS)-4-({[dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-5-(tetrahydro-2H-pyran-2-yloxy)hexahydro-2H-cyclopenta[b]furan-2-one 
• 62447-84-1 (3aR,4S,5S,6R,6aR)-4-Benzyloxymethyl-6-iodo-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one 
• 31767-37-0 6-Benzyloxymethyl-7-hydroxy-8-iodo-2-oxabicyclo<3.3.0>octan-3-one 
• 114647-58-4 [(1R,2S,3R)-2-Nitromethyl-5-oxo-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-acetic acid methyl ester 
• 114647-67-5 (3R,1'R)-5-(1'-carboxy-3'-methylbutoxy)imino-3-hydroxy-1-cyclopentene-1-acetic acid methyl ester 
• 53813-10-8 (3aR,4S,5R,6aS)-4-Nitromethyl-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one 
• 947752-04-7 [(R)-5-Oxo-3-(tetrahydro-pyran-2-yloxy)-cyclopent-1-enyl]-acetic acid methyl ester 
• 114716-07-3 (R)-2-methoxycarbonylmethyl-4-hydroxy-2-cyclopenten-1-one 
• 88147-21-1 2-methoxycarbonylmethyl-4-hydroxy-2-cyclopenten-1-one 
• 57026-61-6 5-oxo-1-cyclopenten-1-acetic acid methyl ester 
• 110-87-2 3,4-dihydro-2H-pyran 
• 32233-41-3 (3aR,4R,5R,6aS)-hexahydro-2-oxo-5-<(tetrahydro-2H-pyran-2-yl)oxy>-2H-cyclopentafuran-4-carboxaldehyde 

Downstream Products

• 32233-40-2 (3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one 
• 65025-95-8 (3aR,4S,5R,6aS)-4-({[dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-5-(tetrahydro-2H-pyran-2-yloxy)hexahydro-2H-cyclopenta[b]furan-2-one 
• 773825-80-2 7,7-difluoro-16S,20-dimethyl-18,19-didehydro prostaglandin I₂ 
• 256382-23-7 5-thia-16-(3-methoxymethylphenyl)methylPGE₁ 
• 256382-08-8 Rivenprost 
• 256382-45-3 16-(3-methoxymethyl)phenyl-ω-tetranor-5-thiaprostaglandin F₁ methyl ester 11,15-bis(tetrahydropyran-2-yl ether) 
• 256382-40-8 6-{(1E)-4-[3-(methoxymethyl)phenyl]-3-oxobut-1-enyl}-7-(2H-3,4,5,6-tetrahydropyran-2-yloxy)(5S,7S,1R,6R)-2-oxabicyclo[3.3.0]octan-3-one 
• 256382-41-9 6-{(1E)(3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]but-1-enyl}-7-(2H-3,4,5,6-tetrahydropyran-2-yloxy)(5S,7S,1R,6R)-2-oxabicyclo[3.3.0]octan-3-one 
• 256382-42-0 6-{(1E)(3S)-3-(2H-3,4,5,6-tetrahydropyran-2-yloxy)-4-[3-(methoxymethyl)phenyl]but-1-enyl}-7-(2H-3,4,5,6-tetrahydropyran-2-yloxy)(5S,7S,1R,6R)-2-oxabicyclo[3.3.0]octan-3-one 
• 457955-36-1 11(R),15(S)-bis(tetrahydro-2-pyranyloxy)-5,9(S)-dihydroxy-16-(3-methoxymethyl)phenyl-1,2,3,4,17,18,19,20-octanorprostanoic acid 
• 256382-46-4 16-(3-methoxymethyl)phenyl-ω-tetranor-5-thiaprostaglandin E₁ methyl ester 11,15-bis(tetrahydropyran-2-yl ether) 
• 443796-72-3 Toluene-4-sulfonic acid (E)-6-[(1R,2S,3R,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-chloro-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hex-4-enyl ester 
• 1262872-82-1 isopropyl 4-[(3S,5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxy-but-1-enyl]-3,4,5,5a,6,7,8,8a-octahydro-2H-cyclopenta[b]oxepin-3-yl]butanoate 
• 1262872-80-9 2-propanyl 4-[(3S,5aR,6R,7R,8aS)-6-[(1E)-3-oxo-4-phenoxy-1-buten-1-yl]-7-(tetrahydro-2H-pyran-2-yloxy)octahydro-2H-cyclopenta[b]oxepin-3-yl]butanoate 

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