693-03-8

Basic information

• Product Name: N-BUTYLMAGNESIUM BROMIDE
• Synonyms: N-BUTYLMAGNESIUM BROMIDE;bromobutylmagnesium;n-Butylmagnesium Bromide 1.0 M In Tetrahydrofuran;n-Butylmagnesium Bromide 3.0 M In Diethyl Ether;Magnesium, bromobutyl-;Butylbromomagnesium;n-Butylmagnesium bromide 1M solution in THF;n-Butylmagnesium bromide 3M solution in DEE
• CAS NO: 693-03-8
• Molecular Formula: C₄H₉BrMg
• Molecular Weight: 161.32
• EINECS: 211-737-4
• Mol File: 693-03-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 80.5-81 °C
• Boiling Point: 128-131 °C(Press: 0.2 Torr)
• Appearance: /
• CAS DataBase Reference: N-BUTYLMAGNESIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BUTYLMAGNESIUM BROMIDE(693-03-8)
• EPA Substance Registry System: N-BUTYLMAGNESIUM BROMIDE(693-03-8)

Safety Data

• RIDADR: 3399
• HazardClass: 4.3/3
• PackingGroup: I
• Hazardous Substances Data: 693-03-8(Hazardous Substances Data)

Usage

General Description

N-butylnagnesium bromide is a chemical compound composed of a magnesium atom bonded to a butyl group and a bromine atom. It is commonly used as a strong nucleophile and a powerful base in organic synthesis. N-BUTYLMAGNESIUM BROMIDE is a valuable reagent in the Grignard reaction, which is a fundamental method for the formation of carbon-carbon bonds in organic chemistry. N-butylnagnesium bromide is also utilized in the production of pharmaceuticals, agrochemicals, and fine chemicals. It is typically stored and handled under inert atmospheres due to its high reactivity with air and moisture. Overall, N-butylnagnesium bromide plays a crucial role in the field of organic chemistry and is a versatile tool in the synthesis of complex organic molecules.

InChI:InChI=1/C4H9.BrH.Mg/c1-3-4-2;;/h1,3-4H2,2H3;1H;/q;;+1/p-1/rC4H9BrMg/c1-2-3-4-6-5/h2-4H2,1H3

Upstream product

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Relevant articles and documents

4-Alkyl-3-azidomethyl-2-ethoxy-2,5-dihydro-5 H-1,2-oxaphosphole 2-Oxides: Synthesis and 1,3-Cycloaddition

Starting from phosphorylated allenes, a three-steps synthesis of a new class of organic azides with a 1,2-oxaphospholene carbon skeleton has been developed. The series of obtained 4-alkyl-3-azidomethyl-2-ethoxy-2,5-dihydro-5H-1,2-oxaphosphole 2-oxides were utilized in the 1,3-cycloaddition with alkyl 2-[1-(propyn-2-yl)-1H-indol-3-yl]-2-oxoacetates for the synthesis of conjugates, which are potentially active cytostatics.

PROCESS FOR THE PREPARATION OF GRIGNARD COMPOUNDS

The invention relates to a process for the preparation of Grignard compounds using a continuous method which involves the reaction of an organic halide dissolved in an organic solvent with metallic magnesium which, together with the activator solution in an organic solvent, fills the flow reactor or optionally a system of flow reactors, and subsequently, the resulting reaction mixture is fed into the terminal flow reactor containing metallic magnesium in order to achieve complete conversion of the organic halide, whereby preferably the organic solvent is re-circulated to flow reactors in a form of vapour.

CONTROL OF PARASITES IN ANIMALS BY THE USE OF IMIDAZO[1,2-B]PYRIDAZINE DERIVATIVES

Novel imidazo[1,2-b]pyridazine compounds useful for controlling parasites in animals and methods of treatment of parasite infestation in animals using the compounds are disclosed. Formula (I).