6936-48-7

Basic information

• Product Name: N-METHYLMALEAMIC ACID
• Synonyms: N-METHYL MALEAMATE;N-METHYLMALEAMIC ACID;N-METHYLMALEIC ACID MONOAMIDE;TIMTEC-BB SBB005847;3-(METHYLAMINOCARBONYL)ACRYLIC ACID;(N-methylcarboxamido)propenoic acid;Maleic acid monomethylamide;N-Methylmaleic Acid
• CAS NO: 6936-48-7
• Molecular Formula: C₅H₇NO₃
• Molecular Weight: 129.11
• EINECS: 230-062-6
• Mol File: 6936-48-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 144-147 °C
• Boiling Point: 239.15°C (rough estimate)
• Flash Point: 183.5°C
• Appearance: /
• Density: 1.3816 (rough estimate)
• Vapor Pressure: 8.12E-07mmHg at 25°C
• Refractive Index: 1.4220 (estimate)
• BRN: 1905722
• CAS DataBase Reference: N-METHYLMALEAMIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYLMALEAMIC ACID(6936-48-7)
• EPA Substance Registry System: N-METHYLMALEAMIC ACID(6936-48-7)

Safety Data

• Statements: 36/37/38
• Safety Statements: 24/25
• Hazardous Substances Data: 6936-48-7(Hazardous Substances Data)

Usage

Chemical Properties

WHITE TO SLIGHTLY YELLOW CHUNKS

InChI:InChI=1/C5H7NO3/c1-6-4(7)2-3-5(8)9/h2-3H,1H3,(H,6,7)(H,8,9)/p-1

Upstream product

• 108-31-6 maleic anhydride 
• 930-88-1 N-methylmaleimide 
• 74-89-5 methylamine 

Downstream Products

• 126364-17-8 3-(3,5-Dichloro-4-methyl-benzenesulfonyl)-1-methyl-pyrrolidine-2,5-dione 
• 126364-16-7 3-(4-Chloro-benzenesulfonyl)-1-methyl-pyrrolidine-2,5-dione 
• 74894-67-0 1-Methyl-3-(toluene-4-sulfonyl)-pyrrolidine-2,5-dione 
• 126364-23-6 1-Methyl-3-(p-chlor-phenylthio)-pyrrolidin-2,5-dion 
• 126364-24-7 1-Methyl-3-phenylthio-pyrrolidin-2,5-dion 
• 1786-73-8 1-Methyl-3-(4-chlor-phenylthio)-pyrrol-2,5-dion 
• 110-17-8 (2E)-but-2-enedioic acid 
• 74-89-5 methylamine 
• 110-16-7 maleic acid 
• 930-88-1 N-methylmaleimide 

Relevant articles and documents

Synthesis and antifungal activity of N-(alkyl/aryl)-2-(3-oxo-1,4- benzothiazin-2-yl)acetamide

A series of N-(alkyl/aryl)-2-(3-oxo-1,4-benzothiazin-2-yl)acetamide have been synthesized by condensation of substituted amines with maleic anhydride (MA) followed by cyclization with o-aminothiophenol (o-ATP). All the compounds have been screened for their antifungal activity against Tricophyton rubrum, Epidermophyton floccosum and Malassazia furfur. In the primary screening, some of the compounds exhibited appreciable activity. The structures of the synthesized compounds 7a-z have been established on the basis of elemental analysis and spectral data.

The Elusive Antiaromaticity of Maleimides and Maleic Anhydride: Enthalpies of Formation of N-Methylmaleimide, N-Methylsuccinimide, N-Methylphthalimide, and N-Benzoyl-N-methylbenzamide

In order to understand the antiaromaticity of maleimides, the enthalpies of formation and sublimation of N-methylmaleimide, N-methylsuccinimide, N-methylphthalimide, and N-benzoyl-N-methylbenzamide were measured. The numerical values of enthalpies of formation for these compounds in the solid state are -329,3 ± 1.4, -469.8 ± 1.6, -325.0 ± 2.1, and -239.6 ± 3.8 kJ mol-1, respectively, while the corresponding values in the gaseous state are -256.0 ± 1.5, -389.7 ± 1.6, -233.9 ± 2.2, and -119.5 ± 3.8 kJ mol-1, respectively. The values of enthalpies of sublimation for the same compounds are 73.3 ± 0.5, 80.1 ± 0.3, 91.1 ± 0.5, and 120.1 ± 0.4 kJ mol-1, respectively. We find that the antiaromaticity of maleimides is only modest.