69388-78-9

Basic information

• Product Name: (2S,5R)-Benzyl 3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylate 4,4-Dioxide
• Synonyms: (2S,5R)-Benzyl 3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylate 4,4-Dioxide
• CAS NO: 69388-78-9
• Molecular Weight: 323.37
• Mol File: 69388-78-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (2S,5R)-Benzyl 3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylate 4,4-Dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5R)-Benzyl 3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylate 4,4-Dioxide(69388-78-9)
• EPA Substance Registry System: (2S,5R)-Benzyl 3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylate 4,4-Dioxide(69388-78-9)

Safety Data

• Hazardous Substances Data: 69388-78-9(Hazardous Substances Data)

Upstream product

• 69388-84-7 sodium sulbactam 
• 100-39-0 benzyl bromide 
• 62263-72-3 (2S,5R)-Benzyl 3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 124831-33-0 (2R,5R)-Benzyl 3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 124831-32-9 (3S,4R)-4-<<4-(Benzyloxy)-2-methyl-4-nitro-3(Z)-buten-2-yl>thio>-1-(tert-butyldimethylsilyl)-3-(trimethylsilyl)-2-azetidinone 
• 128971-81-3 (3S,4R)-4-<<4-(Benzyloxy)-3-hydroxy-2-methyl-4-nitro-2-butyl>thio>-1-(tert-butyldimethylsilyl)-3-(trimethylsilyl)-2-azetidinone 
• 124831-31-8 (3S,4R)-1-(tert-Butyldimethylsilyl)-4-<(2-methyl-3-oxo-2-propyl)thio>-3-(trimethylsilyl)-2-azetidinone 
• 128971-80-2 (3S,4R)-1-(tert-Butyldimethylsilyl)-4-<(2-methyl-3-buten-2-yl)thio>-3-(trimethylsilyl)-2-azetidinone 
• 128971-79-9 (3S,4R)-4-<(2-Methyl-3-buten-2-yl)thio>-3-(trimethylsilyl)-2-azetidinone 
• 551-16-6 6-Aminopenicillanic Acid 
• 62263-89-2 Benzyl 6α-bromopenicillanate 
• 24138-28-1 6-bromopenicillanic acid 
• 76454-56-3 benzyl bromopenicillanate-S,S-dioxide 
• 35564-99-9 benzyl 6,6-dibromopenicillanate 

Downstream Products

• 90473-64-6 (2R,4S)-2-Carboxymethyl-5,5-dimethyl-1,1-dioxo-3-(2,2,2-trifluoro-acetyl)-1λ⁶-thiazolidine-4-carboxylic acid benzyl ester 
• 97129-34-5 Sodium; (R)-1-(1-benzyloxycarbonyl-2-methyl-propenyl)-4-oxo-azetidine-2-sulfinate 
• 97129-35-6 benzyl 2-<(2R)-2-acetonylsulphonyl-4-oxo-azetidin-1-yl>-3-methylbut-2-enoate 
• 97129-36-7 benzyl 2-<(2R)-2-acetonylsulphonyl-4-oxoazetidin-1-yl>glyoxylate 
• 97129-37-8 (6R)-4-benzyloxycarbonyl-3-methylceph-3-em 1,1-dioxide 
• 97129-33-4 (2R)-1-(1-benzyloxycarbonyl-2-methylprop-1-enyl)-4-oxoazetidine-2-sulphinic acid 
• 68373-14-8 sulbactum 

Relevant articles and documents

Total syntheses of penicillanic acid s,s-dioxide and 6-aminopenicillanic acid using(benzyloxy)nitromethane

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The synthesis of penicillanate esters from ultrasonically formed organozinc intermediates

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Total Synthesis of Analogues of the &β-Lactam Antibiotics. Part 2. Isopenam-3-carboxylates and their 2,2-Dioxides

t-Butyl hydroxy-(2-iodomethyl-4-oxoazetidin-1-yl)acetate (10a), as a 1:1 mixture of diastereoisomers, was transformed, by sequential reactions involving thionyl chloride - 2,6-lutidine and hydrogen sulphide - triethylamine, into a 1:1.7 mixture of t-butyl