6942-36-5

Basic information

• Product Name: Methyl 2-bromo-5-nitrobenzoate
• Synonyms: METHYL 2-BROMO-5-NITROBENZOATE;METHYL 2-BROMO-5-NITROBENZOIC ACID;2-BROMO-5-NITROBENZOIC ACID METHYL ESTER;Methyl 2-bromo-5-nitrobenzoate, 98+%
• CAS NO: 6942-36-5
• Molecular Formula: C₈H₆BrNO₄
• Molecular Weight: 260.04
• EINECS: -0
• Product Categories: Aromatic Esters;Acids & Esters;Bromine Compounds;Nitro Compounds;C8 to C9;Carbonyl Compounds;Esters;Building Blocks;C8 to C9;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 6942-36-5.mol
• Article Data: 10

Chemical Properties

• Melting Point: 79-81 °C(lit.)
• Boiling Point: 326.7 °C at 760 mmHg
• Flash Point: 151.4 °C
• Appearance: Yellow/Crystalline Powder
• Density: 1.673 g/cm³
• Vapor Pressure: 0.000212mmHg at 25°C
• Refractive Index: 1.587
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, DCM. Ethyl Acetate
• BRN: 2617575
• CAS DataBase Reference: Methyl 2-bromo-5-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-bromo-5-nitrobenzoate(6942-36-5)
• EPA Substance Registry System: Methyl 2-bromo-5-nitrobenzoate(6942-36-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 6942-36-5(Hazardous Substances Data)

Usage

Chemical Properties

yellow crystalline powder

Uses

Methyl 2-bromo-5-nitrobenzoate may be used in chemical synthesis.

InChI:InChI=1/C8H6BrNO4/c1-14-8(11)6-4-5(10(12)13)2-3-7(6)9/h2-4H,1H3

Upstream product

• 67-56-1 methanol 
• 943-14-6 2-bromo-5-nitrobenzoic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 610-94-6 2-bromobenzoic acid methyl ester 

Downstream Products

• 223767-08-6 methyl 3-nitro-6-(4-fluorobenzyl)benzoate 
• 6942-37-6 5-amino-2-bromo-benzoic acid methyl ester 
• 439937-53-8 methyl 5-nitro-2-vinylbenzoate 
• 1572936-70-9 2-(4-fluoronaphthalen-1-ylamino)-5-nitrobenzoic acid 
• 1572936-82-3 N-((3-methoxy)-2-naphthyl)-5-nitroanthranilic acid 
• 60042-00-4 2-anilino-5-nitro-benzoic acid methyl ester 

Relevant articles and documents

Synthesis and photophysical properties of isocoumarin-based D-π-A systems

We prepared a small library of polarity-sensitive fluorescent dyes characterized by an isocoumarin core properly functionalized with a conjugated push-pull system. The key step of the synthesis is based on a regio-selective silver(I)/p-TSA co-catalyzed cyclization of 2-alkynylbenzoates recently optimized in our laboratory. The photophysical properties of isocoumarin-based D-π-A systems have been investigated and a rationale was proposed based on their dipole moments and Hammett constants of the ED and EW groups involved.

4,4-DIFLUORO-PIPERIDINE-COMPOUNDS

The invention, in a first aspect relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein R is a 6-membered aromatic ring, or a 5- or 6-membered heteroaromatic ring comprising 1 to 3 heteroatoms selected from S, O and N,

Supramolecular control of selectivity in hydroformylation of vinyl arenes: Easy access to valuable β-aldehyde intermediates

Go against the flow! A rationally designed regioselective hydroformylation catalyst, [Rh/L], in which noncovalent ligand-substrate interactions allow the unprecedented reversal of selectivity from the typical α-aldehyde to the otherwise unfavored product β-aldehyde, is reported. This catalytic system opens up novel and sustainable synthetic pathways to important intermediates for the fine-chemicals industry.