6946-15-2

Basic information

• Product Name: 3-HYDROXY-4-METHYL-2-NITROBENZOIC ACID
• Synonyms: Einecs 230-105-9;2-NITRO-3-HYDROXY-4-METHYL-BENZOIC ACID;3-HYDROXY-4-METHYL-2-NITROBENZOIC ACID
• CAS NO: 6946-15-2
• Molecular Formula: C₈H₇NO₅
• Molecular Weight: 197.14
• EINECS: 230-105-9
• Product Categories: C8;Carbonyl Compounds;Carboxylic Acids;Building Blocks;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Organic Building Blocks
• Mol File: 6946-15-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 185-187 °C(lit.)
• Boiling Point: 379.7 °C at 760 mmHg
• Flash Point: 171.1 °C
• Appearance: /
• Density: 1.534 g/cm³
• Vapor Pressure: 1.92E-06mmHg at 25°C
• Refractive Index: 1.642
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.24±0.25(Predicted)
• CAS DataBase Reference: 3-HYDROXY-4-METHYL-2-NITROBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-HYDROXY-4-METHYL-2-NITROBENZOIC ACID(6946-15-2)
• EPA Substance Registry System: 3-HYDROXY-4-METHYL-2-NITROBENZOIC ACID(6946-15-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 6946-15-2(Hazardous Substances Data)

Usage

General Description

3-Hydroxy-4-methyl-2-nitrobenzoic acid is a chemical compound with the molecular formula C8H7NO5. It is a derivative of benzoic acid and contains a hydroxyl group, a methyl group, and a nitro group attached to the benzene ring. 3-HYDROXY-4-METHYL-2-NITROBENZOIC ACID is commonly used in the pharmaceutical industry for its antimicrobial properties and is also used as a building block in the synthesis of various organic compounds. Additionally, it has been studied for its potential application in the development of novel materials and as a fluorescent probe for sensing and imaging applications.

InChI:InChI=1/C8H7NO5/c1-4-2-3-5(8(11)12)6(7(4)10)9(13)14/h2-3,10H,1H3,(H,11,12)

Upstream product

• 57281-77-3 3-methoxy-4-methyl-2-nitro-benzoic acid 
• 3816-66-8 3-hydroxy-4-methylbenzonitrile 
• 7356-52-7 3-acetylamino-4-methyl-2-nitrobenzoic acid 

Downstream Products

• 71788-49-3 methyl 3-hydroxy-4-methyl-2-nitrobenzoate 
• 552-14-7 2-amino-3-hydroxy-4-methylbenzoic acid 
• 159301-22-1 3-hydroxy-4-methyl-2-nitro-N-(cyanoethyl)benzamide 
• 63435-38-1 N-dodecyl-2-nitro-3-hydroxy-4-methylbenzamide 
• 128450-32-8 methyl 3-methoxy-4-methyl-2-nitrobenzoate 
• 1224373-37-8 2-(3-(-(S)-5-((S)-1-amino-3-(3-chlorophenyl)-1-oxopropan-2-ylamino)-4-(3-hydroxy-4-methyl-2-nitrobenzamido)-5-oxopentylcarbamoyl)-phenoxy)acetic acid 
• 1224373-38-9 2-(3-(3-((R)-3-((S)-1-amino-3-(3-chlorophenyl)-1-oxopropan-2-ylamino)-2-(3-hydroxy-4-methyl-2-nitrobenzamido)-3-oxopropylthio)propylcarbamoyl)phenoxy)acetic acid 
• 1224373-42-5 N-((S)-1-((S)-1-amino-3-(3-chlorophenyl)-1-oxopropan-2-ylamino)-1-oxopropan-2-yl)-3-hydroxy-4-methyl-2-nitrobenzamide 
• 1224373-41-4 N-((S)-6-amino-1-((S)-1-amino-3-(3-chlorophenyl)-1-oxopropan-2-ylamino)-1-oxohexan-2-yl)-3-hydroxy-4-methyl-2-nitrobenzamide 
• 28649-32-3 C₁₅H₁₂⁽²⁾HNO₅ 
• 28649-31-2 6-deuterio-3-hydroxy-4-methyl-2-nitro-benzoic acid methyl ester 
• 28649-30-1 4-deuterio-6-nitro-o-cresol 
• 14184-79-3 2-amino-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid dianilide 
• 121758-44-9 C₂₁H₁₅F₃N₂O₆S 

Relevant articles and documents

SUBSTITUTED 2-AMINO-FUSED HETEROCYCLIC COMPOUNDS

The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein: R1, R2, Z1, t, and ring A are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of JNK, such as diabetes, the method comprising administering to a mammal an effective amount of a compound of formula (I).