69501-35-5Relevant articles and documents
Phenolic glycosides from the twigs of Salix glandulosa
Kim, Chung Sub,Kwon, Oh Wook,Kim, Sun Yeou,Choi, Sang Un,Kim, Jae Yoon,Han, Ji Young,Choi, Soo Im,Choi, Jong Gil,Kim, Ki Hyun,Lee, Kang Ro
, p. 1955 - 1961 (2014/10/16)
As a part of an ongoing search for bioactive constituents from Korean medicinal plants, the phytochemical investigations of the twigs of Salix glandulosa afforded 12 new phenolic glycosides (1-12) and a known analogue (13). The structures of 1-13 were characterized by a combination of NMR methods (1H and 13C NMR, 1H-1H COSY, HMQC, and HMBC), chemical hydrolysis, and GC/MS. The absolute configuration of 13 [(1R,2S)-2-hydroxycyclohexyl-2′-O-trans-p-coumaroyl-β-d- glucopyranoside] was determined for the first time. Compounds 1-3, 6, and 7 exhibited inhibitory effects on nitric oxide production in lipopolysaccharide- activated murine microglial cells (IC50 values in the range 6.6-20.5 μM).
Stereochemical Studies of Enzymatic Transglycosylation using Sulfolobus solfataricus
Trincone, Antonio,Nicolaus, Barbara,Lama, Licia,Gambacorta, Agata
, p. 2841 - 2844 (2007/10/02)
Stereochemistry of β-glycosyl transfer from phenyl β-D-galactoside, lactose, and phenyl β-D-glucoside to various 1,2-, 1,3-, and 1,4-diols, a secondary-tertiary diol, a cyclic diol, and a racemic alkohol has been studied using β-glycosidase activity in a crude preparation from the thermophilic archaebacterium Sulfolobus solfataricus.Good enantioselection for the galactosyl transfer to the secondary hydroxy group of different 1,2-diols has been observed.Good yields in comparison with enzymes from other sources, and results concerning the reaction's regioselectivity, have also been reported.
STEREOSPECIFIC PREPARATION OF MONOGLUCOSIDES OF OPTICALY ACTIVE trans-1,2-CYCLOHEXANEDIOLS BY ENZYMIC TRANS-D-GLUCOSYLATION, AND (13)C-N.M.R. SPECTROSCOPY OF THE RESULTING MONO-D-GLUCOPYRANOSIDES
Itano, Kayoko,Yamasaki, Kazuo,Kihara, Chikako,Tanaka, Osamu
, p. 27 - 34 (2007/10/02)
Anomeric mono-D-glucosides of optically active trans-1,2-cyclohexanediols were stereoselectively prepared from the racemic mixture by means of enzymic trans-D-glucosylation using crude enzyme preparations that are commercially available or are utilized for food manufacturing.The (13)C-n.m.r. spectra of these D-glucosides were characterized, and the stereochemical influence, on the glycosylation shifts of cyclohexanol, of the vicinal hydroxyl substitution was discussed in comparison with that of vicinal alkyl substitution reported previously.