6955-57-3Relevant articles and documents
Metal-Free Synthesis of N-Aryl-Substituted Azacycles from Cyclic Ethers Using POCl3
La, Minh Thanh,Kang, Soosung,Kim, Hee-Kwon
, p. 6689 - 6696 (2019/06/14)
A facile method for the synthesis of N-aryl-substituted azacycles from arylamines and cyclic ethers has been developed. In this study, arylamines were treated with cyclic ethers in the presence of POCl3 and DBU to provide five- A nd six-membered azacycles. Using this method, various azacycloalkanes, isoindolines, and tetrahydroisoquinolines were prepared in high yields. This synthetic method offers an efficient approach to the production of azacycles from cyclic ethers.
2-AMINO-1,3,2λ5-OXAZAPHOSPHORINANE 2-OXIDES
Uryupin, A. B.,Kadyko, M. I.,Petrovskii, P. V.,Okruszek, A.,Kinas, R.,et al.
, p. 1433 - 1437 (2007/10/03)
1,3,2λ5- oxazaphosphorinane 2-oxide derivatives were obtained by phosphorylation of amines and amino acid esters.A method for synthesizing pure enantiomers of 2-phenylamino-1,3,2λ5-oxazaphosphorinane 2-oxide was elaborated.
Synthesis and properties of bis(2,2-dimethylaziridinyl)phosphinic amides: A series of new antineoplastic agents
MacDiarmid,Rose,Biddle,Perlman,Breiner,Ambrus,Bardos
, p. 1685 - 1691 (2007/10/02)
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