69709-41-7

Basic information

• Product Name: Benzene, [(1-chloropropyl)sulfonyl]-
• CAS NO: 69709-41-7
• Molecular Formula: C9H11ClO2S
• Molecular Weight: 218.704
• Mol File: 69709-41-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzene, [(1-chloropropyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(1-chloropropyl)sulfonyl]-(69709-41-7)
• EPA Substance Registry System: Benzene, [(1-chloropropyl)sulfonyl]-(69709-41-7)

Safety Data

• Hazardous Substances Data: 69709-41-7(Hazardous Substances Data)

Upstream product

• 131454-22-3 1-phenyl-2-(phenylsulfonyl)butan-1-one 
• 3406-03-9 2-(phenylsulfonyl)acetophenone 
• 117841-07-3 erythro-2-chloro-1-phenyl-2-phenylsulfonylbutanol 
• 117841-07-3 threo-2-chloro-1-phenyl-2-phenylsulfonylbutanol 
• 117841-25-5 2-chloro-2-phenylsulfonyl-1-phenylbutanone 
• 7205-98-3 chloromethyl phenyl sulfone 
• 13557-25-0 1-(1-chloroethyl)phenyl sulfone 
• 98-95-3 nitrobenzene 

Downstream Products

• 69709-35-9 1-(1-Benzenesulfonyl-propyl)-4-nitro-benzene 
• 117461-11-7 1-(5-chloro-2-nitrophenyl)propyl phenyl sulphone 
• 1395320-35-0 2-ethyl-4-nitro-7-[1-(phenylsulfonyl)propyl]-2H-indazole 
• 1395320-33-8 2-ethyl-4-nitro-5-[1-(phenylsulfonyl)propyl]-2H-indazole 
• 1395320-37-2 1-ethyl-7-nitro-4-[1-(phenylsulfonyl)propyl]-1H-indazole 
• 1395320-25-8 1-methyl-4-nitro-7-[1-(phenylsulfonyl)propyl]-1H-indazole 
• 1395320-27-0 1-ethyl-4-nitro-7-[1-(phenylsulfonyl)propyl]-1H-indazole 
• 1395320-45-2 1-ethyl-7-nitro-4-[1-(phenylsulfonyl)propyl]-1H-benzotriazole 
• 1395320-43-0 2-ethyl-4-nitro-7-[1-(phenylsulfonyl)propyl]-2H-benzotriazole 
• 1395320-41-8 2-ethyl-4-nitro-5-[1-(phenylsulfonyl)propyl]-2H-benzotriazole 
• 1395320-39-4 1-ethyl-4-nitro-7-[1-(phenylsulfonyl)propyl]-1H-benzotriazole 
• 1262337-18-7 6-chloro-1,2,4-triazolo[4,3-b]pyridazin-3-ylmethyl acetate 
• 1262337-17-6 6-chloro-3-chloromethyl-8-[1-(phenylsulfonyl)propyl]-1,2,4-triazolo[4,3-b]pyridazine 
• 117841-08-4 E-1,2-epoxy-1-phenyl-2-phenylsulfonylbutane 

Relevant articles and documents

Chemoselective mono halogenation of β-keto-sulfones using potassium halide and hydrogen peroxide; synthesis of halomethyl sulfones and dihalomethyl sulfones

The synthesis of α-halo β-keto-sulfones using potassium halide and hydrogen peroxide as a chemoselective mono halogenation reagent and the synthesis of α,α-symmetrical and asymmetrical dihalo β-keto-sulfones and α-halo, α-alkyl and β-keto-sulfones is described. Base induced cleavage of α-halo β-keto-sulfones, α,α-dihalo β-keto-sulfones, and α-halo, α-alkyl β-keto-sulfones afforded the corresponding halomethyl sulfones, dihalomethyl sulfones and haloalkyl sulfones.

VICARIOUS NUCLEOPHILIC SUBSTITUTION OF HYDROGEN ORTHO TO THE NITRO GROUP BY TERTIARY CARBANIONS OF α-CHLOROALKYL PHENYL SULPHONES

The tertiary carbanions of α-chloroalkyl phenyl sulphones readily enter the vicarious nucleophilic substitution of hydrogen ortho to the nitro group with a number of 4- and 3-substituted nitrobenzenes, when potassium tert-butoxide/DMF base-solvent system at -40 deg C + -30 deg C is employed.