69747-55-3 Usage
Description
1-Stearoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (also known as Stearoyl Lysophosphatidylethanolamine) is a lysophospholipid that plays a significant role in cellular signaling and has been identified as a lipid biomarker for the diagnosis of cancer. It is characterized by its ability to induce transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) receptor antagonist AM095.
Uses
Used in Diagnostic Applications:
1-Stearoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine is used as a lipid biomarker for the diagnosis of cancer. Its presence in biological samples can indicate the presence of cancerous cells, aiding in the early detection and monitoring of the disease.
Used in Pharmaceutical Research:
As a lysophospholipid, 1-Stearoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine may also be utilized in the development of novel therapeutic agents targeting cancer cells. Its ability to modulate intracellular calcium levels and interact with specific receptors, such as LPA1, could potentially be harnessed for the design of targeted cancer treatments.
Used in Neurobiological Studies:
Due to its effect on intracellular calcium levels in neuronal cells, 1-Stearoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine may also be employed in neurobiological research to better understand the role of lysophospholipids in neuronal signaling and function.
Used in Lipidomics Research:
1-Stearoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine can be a valuable compound in the field of lipidomics, which focuses on the comprehensive analysis of lipids and their role in various biological processes. Its study can contribute to the understanding of lipid metabolism, cellular signaling, and the development of new biomarkers for various diseases, including cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 69747-55-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,7,4 and 7 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 69747-55:
(7*6)+(6*9)+(5*7)+(4*4)+(3*7)+(2*5)+(1*5)=183
183 % 10 = 3
So 69747-55-3 is a valid CAS Registry Number.
