698-72-6

Basic information

• Product Name: 2,4-dichloro-6-ethyl-1,3,5-triazine
• Synonyms: 2,4-dichloro-6-ethyl-1,3,5-triazine;2,4-DICHLORO-6-ETHYL-S-TRIAZINE
• CAS NO: 698-72-6
• Molecular Formula: C₅H₅Cl₂N₃
• Molecular Weight: 178.02
• Mol File: 698-72-6.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 346.3°C at 760 mmHg
• Flash Point: 194.1°C
• Appearance: /
• Density: 1.414g/cm³
• Vapor Pressure: 0.000116mmHg at 25°C
• Refractive Index: 1.546
• CAS DataBase Reference: 2,4-dichloro-6-ethyl-1,3,5-triazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dichloro-6-ethyl-1,3,5-triazine(698-72-6)
• EPA Substance Registry System: 2,4-dichloro-6-ethyl-1,3,5-triazine(698-72-6)

Safety Data

• Hazardous Substances Data: 698-72-6(Hazardous Substances Data)

Usage

General Description

2,4-dichloro-6-ethyl-1,3,5-triazine is a chemical compound with the molecular formula C6H6Cl2N3. It is a white crystalline powder that is commonly used as an herbicide to control undesirable grasses and broadleaf weeds in various crops. It works by inhibiting photosynthesis in the targeted plants, leading to their eventual death. 2,4-dichloro-6-ethyl-1,3,5-triazine is known to have low toxicity to mammals and is considered relatively safe when used as directed. However, it is important to handle and use this chemical with care to minimize potential health and environmental risks.

InChI:InChI=1/C5H5Cl2N3/c1-2-3-8-4(6)10-5(7)9-3/h2H2,1H3

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 925-90-6 ethylmagnesium bromide 
• 74-96-4 ethyl bromide 
• 2386-64-3 ethylmagnesium chloride 

Downstream Products

• 5248-51-1 2-ethyl-4-methoxy-6-morpholino-1,3,5-triazine 
• 26741-04-8 2-ethyl-4,6-bis(cyclohexylamino)-1,3,5-triazine 

Relevant articles and documents

ROCK INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF

The invention relates to a ROCK inhibitor represented by formula (I), its preparation method and its use. The ROCK inhibitor has excellent ROCK inhibition activity, in particular good selective inhibition on ROCK2 kinase, has good safety and metabolic stability, and has high bioavailability. The process of preparing the ROCK inhibitor is simple, and the ROCK inhibitor is easy to purify, and therefore offers good prospects for application.

Glass engineering of aminotriazine-based materials with sub-ambient: T gand high kinetic stability

A challenge in glass engineering is the design of molecular glasses combining a high glass kinetic stability (GS) of the amorphous phase with a low (sub-ambient) glass transition temperature (Tg). Triazine derivatives with arylamino substituents readily form glassy phases that can show outstanding resistance to crystallization. In the present study, a series of 12 analogous compounds incorporating phenylamino and cyclohexylamino groups was synthesized, and their thermal properties and intermolecular interactions were studied. All compounds possess an excellent glass-forming ability, a low Tg ranging from 32 °C to as low as -19 °C, and a high GS. While the cyclohexyl derivatives show higher Tg, the phenyl derivatives possess a higher GS with some compounds remaining completely amorphous for over three years despite their sub-ambient Tg. X-ray diffraction, infrared spectroscopy and DFT calculations reveal that the higher volume occupancy and rotational energy barrier of cyclohexyl groups are the main factors responsible for the compounds' higher Tg values but that they also contribute to their higher propensity to crystallize. In counterpart, the planarity of phenyl groups leads to poorer packing and enhances their GS while keeping their Tg well below ambient. The formation of hydrogen bonds or competing interactions provides an additional handle to tune the Tg of the compounds. Taken together, these studies provide guidelines for the design of molecular glasses with readily tunable thermal properties in view of their functionalization. This journal is

TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS

The invention provides Triazine derivatives and further provides methods of using these compounds to modulate protein kinases and for treating diseases and conditions mediated by protein kinases.