70291-26-8

Basic information

• Product Name: 2-CHLORO-3-PYRROL-1-YLPYRIDINE
• Synonyms: 2-CHLORO-3-(1H-PYRROL-1-YL)PYRIDINE;2-CHLORO-3-PYRROL-1-YLPYRIDINE;BUTTPARK 33\08-75;2-Chloro-3-pyrrol-1-ylpyridi
• CAS NO: 70291-26-8
• Molecular Formula: C₉H₇ClN₂
• Molecular Weight: 178.62
• Mol File: 70291-26-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 92-95°C 0,6mm
• Flash Point: 137.4 °C
• Appearance: /
• Density: 1.23 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-CHLORO-3-PYRROL-1-YLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3-PYRROL-1-YLPYRIDINE(70291-26-8)
• EPA Substance Registry System: 2-CHLORO-3-PYRROL-1-YLPYRIDINE(70291-26-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-41-37/38
• Safety Statements: 26-36/37/39-39
• Hazardous Substances Data: 70291-26-8(Hazardous Substances Data)

Usage

Uses

2-Chloro-3-(1H-pyrrol-1-yl)pyridine is a useful reactant for the synthesis of pyrido[2,?3-?e]?pyrrolo[1,?2-?a]?pyrazine derivatives through tandem iminium cyclization and Smiles rearrangement.

Upstream product

• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 6298-19-7 2-chloro-3-aminopyridine 

Downstream Products

• 104149-51-1 dihydro-5,6 oxo-6 pyrido<2,3-e>pyrrolo<1,2-a>pyrazine 
• 97580-57-9 (chloro-2-pyridyl-3)-1-pyrrolyl-2 carboxaldehyde 

Relevant articles and documents

Synthesis of pyrido[2,3-e]pyrrolo[1,2-a]pyrazine derivatives via tandem iminium cyclization and smiles rearrangement

(Chemical Equation Presented) The tandem iminium cyclization and Smiles rearrangement of pyridinyloxyacetaldehyde 1 and a primary amine generated a novel pyrido[2,3-e]pyrrolo[1,2-a]pyrazine scaffold. TFA was discovered to be an efficient catalyst in the r

REINVESTIGATION OF A CYCLIZATION REACTION OF 2-HYDRAZINO-3-(1H-PYRROL-1-YL)PYRIDINE

The reaction of 2-hydrazino-3-(1H-pyrrol-1-yl)pyridine (3) with acetylacetone affords 2-(3,5-dimethyl-1H-pyrazol-1-yl)-3-(1H-pyrrol-1-yl)pyridine (7) rather than 3,5-dimethyl-10-(1H-pyrrol-1-yl)pyridotriazepine (5), as previously reported.

Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines

Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. These pyridines have pharmaceutical properties such as anti-hypertensive activity of rapid onset.