70419-06-6Relevant articles and documents
Catalytic enantioselective addition of methyltriisopropoxititanium to aldehydes
Veguillas, Marcos,Solà, Ricard,Fernández-Iba?ez, M. ángeles,Maciá, Beatriz
, p. 643 - 648 (2016/07/11)
An efficient catalyst for the enantioselective synthesis of chiral methyl carbinols from aldehydes is presented. The system uses methyltriisopropoxytitanium as a nucleophile and a readily available binaphthyl derivative as a chiral ligand. The enantioselective methylation of both aromatic and aliphatic aldehydes proceeds with good yields and high enantioselectivities under mild conditions.
ALKANE OXIDATION BY MODIFIED HYDROXYLASES
-
Paragraph 0323; 0324, (2016/02/16)
This invention relates to modified hydroxylases. The invention further relates to cells expressing such modified hydroxylases and methods of producing hydroxylated alkanes by contacting a suitable substrate with such cells.
Identification of key residues in Debaryomyces hansenii carbonyl reductase for highly productive preparation of (S)-aryl halohydrins
Xu, Guo-Chao,Shang, Yue-Peng,Yu, Hui-Lei,Xu, Jian-He
supporting information, p. 15728 - 15731 (2015/11/02)
Key residues of Debaryomyces hansenii carbonyl reductase in the determination of the reducing activity towards aryl haloketones were identified through combinatorial mutation of conserved residues. This study provides a green and efficient biocatalyst for the synthesis of (S)-aryl halohydrins.