705-84-0Relevant articles and documents
Organocatalytic Asymmetric Synthesis of Aza-Spirooxindoles via Michael/Friedel-Crafts Cascade Reaction of 1,3-Nitroenynes and 3-Pyrrolyloxindoles
Ni, Qijian,Wang, Xuyang,Zeng, Da,Wu, Qianling,Song, Xiaoxiao
supporting information, p. 2273 - 2278 (2021/04/05)
An asymmetric [3+3] cyclization of nitroenynes and 3-pyrrolyloxindoles has been realized with a chiral bifunctional squaramide catalyst. This Michael/Friedel-Crafts cascade strategy provides a facile and efficient access to enantioenriched polycyclic aza-spirooxindoles with 32-95% isolated yields and excellent stereocontrol under mild reaction conditions.
Catalyst-free sulfa-Michael addition of pyrimidine-2-thiol to nitroolefins
Li, Zheng,Song, Geyang,He, Jiaojiao,Du, Yan,Yang, Jingya
, p. 686 - 698 (2017/09/06)
Catalyst-free sulfa-Michael addition of pyrimidine-2-thiol to nitroolefins is described. A series of 2-((2-nitro-1-arylethyl)thio)pyrimidines were efficiently synthesized. The protocol has advantages of wide range of substituents tolerance, no catalyst, additives and bases, mild condition, and high yield. The method can also extend to gram scale.
NITROETHYLENES AND RELATED COMPOUNDS AS TRICHOMONACIDES AND CANDIDACIDS.
CLITHEROE,GREEN,JANSEN,PHILLIPS,RULE
, p. 167 - 172 (2007/10/09)
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