70547-87-4

Basic information

• Product Name: 2,6-Dimethyl-4-hydroxybenzaldehyde
• Synonyms: TIMTEC-BB SBB008519;2,6-DIMETHYL-4-HYDROXYBENZALDEHYDE;4-HYDROXY-2,6-DIMETHYLBENZALDEHYDE;2,6-Dimethyl-4-hydrobenzaldehyde;4-Hydroxy-2,6-Dimethyl Benzaldehyde 2,6-Dimethyl-4-Hydroxy Benzaldehyde;4-HYROXY-2,6-DIMETHYLBENZALDEHYDE;Benzaldehyde, 4-hydroxy-2,6-dimethyl- (6CI, 7CI, 9CI);2,6-DIMETHYL-4-HYDROXYBENZALDEHEYDE
• CAS NO: 70547-87-4
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.17
• EINECS: 1806241-263-5
• Product Categories: ALDEHYDE;Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde;CHIRAL CHEMICALS
• Mol File: 70547-87-4.mol
• Article Data: 16

Chemical Properties

• Melting Point: 190-196°C
• Boiling Point: 231.72°C (rough estimate)
• Flash Point: 119 °C
• Appearance: /
• Density: 1.0858 (rough estimate)
• Vapor Pressure: 0.0018mmHg at 25°C
• Refractive Index: 1.5180 (estimate)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 8.02±0.23(Predicted)
• CAS DataBase Reference: 2,6-Dimethyl-4-hydroxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethyl-4-hydroxybenzaldehyde(70547-87-4)
• EPA Substance Registry System: 2,6-Dimethyl-4-hydroxybenzaldehyde(70547-87-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 70547-87-4(Hazardous Substances Data)

Usage

General Description

2,6-Dimethyl-4-hydroxybenzaldehyde is a chemical compound also known as para-anisaldehyde. It is an aromatic aldehyde characterized by two methyl groups attached to carbon-2 and carbon-6, respectively, and a hydroxyl group attached to carbon-4 of the benzene ring. The chemical boils at a temperature of 114-117 °C and has a melting point of 56-60 °C. Its synthesis can be accomplished via the reaction of 2,6-Dimethylphenol with formic acid. This chemical is typically used in fragrances due to its sweet, anise-like smell, and it may also serve as an intermediate in the synthesis of other chemicals in pharmaceutical and cosmetic industries.

InChI:InChI=1/C9H10O2/c1-6-3-8(11)4-7(2)9(6)5-10/h3-5,11H,1-2H3

Upstream product

• 80826-86-4 4-iodo-3,5-dimethylphenol 
• 67-66-3 chloroform 
• 108-68-9 3,5-Dimethylphenol 
• 5312-73-2 dichloromethyl n-butyl ether 
• 378185-88-7 tert-butyl(4-iodo-3,5-dimethylphenoxy)dimethylsilane 
• 4885-02-3 Dichloromethyl methyl ether 
• 149228-92-2 (4-bromo-3,5-dimethylphenoxy)(tert-butyl)-di-methylsilane 
• 7463-51-6 4-bromo-3,5-dimethylphenol 
• 378185-89-8 4-(tert-butyldimethylsilanyloxy)-2,6-dimethylbenzaldehyde 
• 7446-70-0 aluminium trichloride 
• 71-43-2 benzene 
• 874-63-5 3,5-dimethylmethoxybenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 557-21-1 dicyanozinc 

Downstream Products

• 899808-19-6 C₁₇H₁₈O₃ 
• 95741-45-0 4-(benzyloxy)-2,6-dimethylbenzoic acid 
• 75056-97-2 2,6-dimethyl-4-hydroxybenzoic acid 
• 37934-89-7 2,6-Dimethyl-4-methoxybenzoic acid 
• 105970-36-3 4-<2,6-dimethyl-4-<(methylsulfonyl)oxy>phenyl>-2-isopropenylbutyl methanesulfonate 
• 105970-33-0 3,5-dimethyl-4-(hydroxymethyl)phenyl methanesulfonate 
• 105970-34-1 5-(2,6-dimethyl-4-hydroxyphenyl)-3-methylidene-2-methyl-2-pentanol 
• 105970-35-2 5-(2,6-dimethyl-4-hydroxyphenyl)-3-(hydroxymethyl)-2-methyl-2-pentanol 
• 111159-87-6 2-<(4-metoxy-2,6-dimethylphenyl)methylene>hydrazinecarboximidamide 
• 185331-30-0 4-Hydroxy-2,6-dimethylbenzaldehyd-(1,1,2-trimethyl-2-nitrosopropyl)-nitron 

Relevant articles and documents

Efficient synthesis and Suzuki cross-coupling reactions of meso-tetrakis(2,6-dimethyl-4-triflyloxyphenyl)porphyrin

An ortho-dimethyl substituted meso-tetrakisarylporphyrin prefunctionalized with triflate groups was prepared in good yield from an accessible 2,6-dimethyl-4-(triflyloxy)benzaldehyde. This porphyrin is an interesting building block, which could directly be

Synthesis of γ-labeled nucleoside 5′-triphosphates using click chemistry

Real-time enzymatic studies are gaining importance as their chemical and technical instrumentation improves. Here we report the efficient synthesis of γ-alkyne modified triphosphate amidates that are converted into a variety of γ-fluorophore labeled triph

New Acyloxymethyl Ketones: Useful Probes for Cysteine Protease Profiling

Peptidyl-acyloxymethyl ketones (AOMKs) belong to a class of selective, irreversible inhibitors (activity-based probes) widely used as chemical tools of investigating proteins, for example, in activity-based protein profiling. The synthesis of the AOMKs has always been challenging and current methodologies involve both solution and solid-phase synthesis. Herein, the synthesis of a new scaffold useful for the preparation of peptidyl-AOMKs is reported and it is demonstrated that the new synthetic probes bearing a 4-functionalized 2,6-dimethylbenzoate efficiently inhibit cysteine proteases like cathepsin B.

A direct and mild formylation method for substituted benzenes utilizing dichloromethyl methyl ether-silver trifluoromethanesulfonate

A silver trifluoromethanesulfonate (AgOTf)-promoted direct and mild formylation of benzenes has been developed. The reaction utilizing dichloromethyl methyl ether (Cl2CHOMe) and AgOTf powerfully formylated various substituted benzenes under temperature conditions as low as -78 C without losing the protecting groups on the phenolic hydroxyl group.