7055-03-0

Basic information

• Product Name: 2-METHYLBENZANILIDE
• Synonyms: O-METHYL BENZANILIDE;O-TOLUANILIDE;2-methylbenzoanilide;2-methylbenzoicacidanilide;2-methyl-n-phenyl-benzamid;2-methyl-n-phenylbenzamide;bas305;bas-3050
• CAS NO: 7055-03-0
• Molecular Formula: C₁₄H₁₃NO
• Molecular Weight: 211.26
• EINECS: 230-334-4
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 7055-03-0.mol
• Article Data: 75

Chemical Properties

• Melting Point: 125°C
• Boiling Point: 350.95°C (rough estimate)
• Flash Point: 162.2oC
• Appearance: /
• Density: 1.0694 (rough estimate)
• Vapor Pressure: 0.00483mmHg at 25°C
• Refractive Index: 1.5780 (estimate)
• PKA: 13.53±0.70(Predicted)
• CAS DataBase Reference: 2-METHYLBENZANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYLBENZANILIDE(7055-03-0)
• EPA Substance Registry System: 2-METHYLBENZANILIDE(7055-03-0)

Safety Data

• Hazardous Substances Data: 7055-03-0(Hazardous Substances Data)

Usage

Uses

o-Toluanilide is a systemic fungicide used in pesticide formulations.

InChI:InChI=1/C14H13NO/c1-11-7-5-6-10-13(11)14(16)15-12-8-3-2-4-9-12/h2-10H,1H3,(H,15,16)

Upstream product

• 131-58-8 2-Methylbenzophenone 
• 118-90-1 ortho-methylbenzoic acid 
• 62-53-3 aniline 
• 10026-13-8 phosphorus pentachloride 
• 85515-91-9 (E)-phenyl(o-tolyl)methanone oxime 
• 615-37-2 ortho-methylphenyl iodide 
• 68971-87-9 (2-tolyl)tributyltin 
• 103-71-9 phenyl isocyanate 
• 16419-60-6 2-Methylphenylboronic acid 
• 141-32-2 acrylic acid n-butyl ester 
• 17922-30-4 N-phenyl-2-(trimethylsilyl)benzamide 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 591-50-4 iodobenzene 
• 529-19-1 2-Methylbenzonitrile 

Downstream Products

• 65786-51-8 (4-(dimethylamino)phenyl)(o-tolyl)methanone 
• 110966-95-5 N-[1-Phenylamino-1-o-tolyl-meth-(E)-ylidene]-benzenesulfonamide 
• 110966-97-7 4-Chloro-N-[1-phenylamino-1-o-tolyl-meth-(E)-ylidene]-benzenesulfonamide 
• 575451-95-5 2-methyl-4'-pyrrolidinobenzophenone 
• 14959-62-7 2-phenyl-3-phenylisoquinolin-1-one 
• 1373208-45-7 C₂₂H₂₅NO₄ 
• 5388-42-1 N-phenylphthalimidine 
• 131-58-8 2-Methylbenzophenone 
• 15903-58-9 2-(o-Tolyl)benzo[d]thiazole 

Relevant articles and documents

Fe-mediated synthesis of: N -aryl amides from nitroarenes and acyl chlorides

Amides are prevalent in nature and valuable functional compounds in agrochemical, pharmaceutical, and materials industries. In this work, we developed a selective and mild method for the synthesis of N-aryl amides. Starting from commercially available nitroarenes and acyl halides, N-aryl amides with good yields can be obtained in water. Especially in the process of transformation, Fe dust is the only reductant and additive, and the reaction can be easily performed on a large scale.

Nickel-Catalyzed Reductive Cross-Coupling of N-Acyl and N-Sulfonyl Benzotriazoles with Diverse Nitro Compounds: Rapid Access to Amides and Sulfonamides

Herein we report a Ni-catalyzed reductive transamidation of conveniently available N-acyl benzotriazoles with alkyl, alkenyl, and aryl nitro compounds, which afforded various amides with good yields and a broad substrate scope. The same catalytic reaction conditions were also applicable for N-sulfonyl benzotriazoles, which could undergo smooth reductive coupling with nitroarenes and nitroalkanes to afford the corresponding sulfonamides.

Regioselective Synthesis of 2° Amides Using Visible-Light-Induced Photoredox-Catalyzed Nonaqueous Oxidative C-N Cleavage of N, N-Dibenzylanilines

A visible-light-driven photoredox-catalyzed nonaqueous oxidative C-N cleavage of N,N-dibenzylanilines to 2° amides is reported. Further, we have applied this protocol on 2-(dibenzylamino)benzamide to afford quinazolinones with (NH4)2S2O8 as an additive. Mechanistic studies imply that the reaction might undergo in situ generation of α-amino radical to imine by C-N bond cleavage followed by the addition of superoxide ion to form amides.