70565-67-2

Basic information

• Product Name: 1,1-Difluoro-3-phenyl-3-<(trimethylsilyl)oxy>-1-butene
• Synonyms: 1,1-Difluoro-3-phenyl-3-<(trimethylsilyl)oxy>-1-butene
• CAS NO: 70565-67-2
• Molecular Weight: 256.368
• Mol File: 70565-67-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,1-Difluoro-3-phenyl-3-<(trimethylsilyl)oxy>-1-butene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Difluoro-3-phenyl-3-<(trimethylsilyl)oxy>-1-butene(70565-67-2)
• EPA Substance Registry System: 1,1-Difluoro-3-phenyl-3-<(trimethylsilyl)oxy>-1-butene(70565-67-2)

Safety Data

• Hazardous Substances Data: 70565-67-2(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 127462-20-8 2-phenyl-2-trimethylsilyloxypropanenitrile 
• 75-61-6 dibromodifluoromethane 
• 70565-65-0 2-Phenyl-2-<(trimethylsilyl)oxy>propanal 

Downstream Products

• 70565-71-8 1,1-Difluoro-3-phenyl-3-methyl-2-butenyl acetate 
• 70565-69-4 4,4-Difluoro-2-phenyl-but-3-en-2-ol 
• 3461-50-5 methyl trans-3-methylcinnamate 
• 54976-38-4 (E)-3-phenylbut-2-en-1-ol 

Relevant articles and documents

Mesyloxy-group migration as the stereoselective preparation method of various functionalized olefins and its reaction mechanism

It was demonstrated that mesylation of appropriate γ,γ-difluorinated allylic alcohols under usual conditions furnished the corresponding α,γ-difluorinated allylic mesylates, possibly by way of 1,3-mesyloxy-group migration after formation of the expected "normal" intermediates, γ,γ-difluorinated allylic mesylates. This rearrangement was conveniently applied to the construction of trisubstituted allylic alcohols, α,β-unsaturated esters, amides, or ketones in good to excellent chemical yields with exclusive E selectivities.