70618-85-8

Basic information

• Product Name: C₁₄H₁₁ClFN₃S
• CAS NO: 70618-85-8
• Molecular Weight: 307.779
• Mol File: 70618-85-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₁ClFN₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₁ClFN₃S(70618-85-8)
• EPA Substance Registry System: C₁₄H₁₁ClFN₃S(70618-85-8)

Safety Data

• Hazardous Substances Data: 70618-85-8(Hazardous Substances Data)

Upstream product

• 22814-92-2 4-(p-chlorophenyl)-3-thiosemicarbazide 
• 459-57-4 4-fluorobenzaldehyde 

Relevant articles and documents

2-Acetylpyridine thiosemicarbazones. 1. A new class of potential antimalarial agents

Based on the antimalarial properties observed for 2-acetylpyridine 4-phenyl-3-thiosemicarbazone (1), an extensive series of related thiosemicarbazones was prepared and tested against Plasmodium berghei in mice. Screening results indicated that the presence of the 2-pyridylethylidene group was critical and that certain phenyl, benzyl, phenethyl, or cycloalkyl groups at N4 of the thiosemicarbazone moiety also contribute to antimalarial activity.