70672-82-1

Basic information

• Product Name: 2(3H)-Benzoxazolone,5-bromo-3-methyl-
• Synonyms: 2(3H)-Benzoxazolone,5-bromo-3-methyl-;5-BROMO-3-METHYLBENZO[D]OXAZOL-2(3H)-ONE;5-bromo-3-methyl-1,3-benzoxazol-2-one
• CAS NO: 70672-82-1
• Molecular Formula: C₈H₆BrNO₂
• Molecular Weight: 228.04274
• Mol File: 70672-82-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 312.7°Cat760mmHg
• Flash Point: 142.9°C
• Appearance: /
• Density: 1.71g/cm³
• Vapor Pressure: 0.00052mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: 2(3H)-Benzoxazolone,5-bromo-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Benzoxazolone,5-bromo-3-methyl-(70672-82-1)
• EPA Substance Registry System: 2(3H)-Benzoxazolone,5-bromo-3-methyl-(70672-82-1)

Safety Data

• Hazardous Substances Data: 70672-82-1(Hazardous Substances Data)

Usage

General Description

2(3H)-Benzoxazolone,5-bromo-3-methyl-, also known as 5-Bromo-3-methyl-2(3H)-benzoxazolone, is a chemical compound with the molecular formula C9H7BrNO2. It is a heterocyclic compound that contains a benzoxazolone ring with a bromo and methyl substituent. 2(3H)-Benzoxazolone,5-bromo-3-methyl- is commonly used in the field of organic synthesis and pharmaceutical research. It has also been studied for its potential biological activities, including its potential as an anti-cancer agent and its ability to inhibit certain enzymes. Additionally, it has been used as a starting material for the synthesis of various pharmacologically active compounds.

InChI:InChI=1/C8H6BrNO2/c1-10-6-4-5(9)2-3-7(6)12-8(10)11/h2-4H,1H3

Upstream product

• 1885-14-9 phenyl chloroformate 
• 857828-66-1 (5-bromo-2-hydroxy-phenyl)-carbamic acid phenyl ester 
• 40925-68-6 2-amino-4-bromo-phenol 
• 14733-73-4 5-bromo-1,3-benzoxazol-2(3H)-one 
• 74-88-4 methyl iodide 

Downstream Products

• 1161500-18-0 tert-butyl (S)-2-((S)-1-amino-3-(4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)-1-oxopropan-2-ylcarbamoyl)piperidine-1-carboxylate 
• 1352152-02-3 (S)-tert-butyl 1-(1-amino-3-(4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)-1-oxopropan-2-ylcarbamoyl)cyclohexylcarbamate 
• 1254319-27-1 (S)-tert-butyl 4-(1-amino-3-(4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)-1-oxopropan-2-ylcarbamoyl)tetrahydro-2H-pyran-4-ylcarbamate 

Relevant articles and documents

AMINO PYRIMIDINE COMPOUND FOR INHIBITING PROTEIN TYROSINE KINASE ACTIVITY

An amino pyrimidine compound for inhibiting protein tyrosine kinase activity, a pharmaceutical composition thereof, preparation therefor, and an application thereof. Specifically, an amino pyrimidine compound represented by formula (I), R1, R2, L, Y, R6, W, A, m, and n being defined in the specification, and a pharmaceutically acceptable salt, a stereoisomer, a solvent compound, a hydrate, a polymorphism, a prodrug, or an isotope variant thereof. The compound can be used for treating and/or preventing protein tyrosine kinase-related diseases such as cell proliferative diseases, cancers, and immune diseases.

BENZOXAZOLONE DERIVATIVES AS ALDOSTERONE SYMTHASE INHIBITORS

The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical comp