70682-98-3

Basic information

• Product Name: PHENYL-QUINOLIN-6-YL-AMINE
• Synonyms: PHENYL-QUINOLIN-6-YL-AMINE
• CAS NO: 70682-98-3
• Molecular Formula: C₁₅H₁₂N₂
• Molecular Weight: 220.26918
• Mol File: 70682-98-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 406.3°C at 760 mmHg
• Flash Point: 199.5°C
• Appearance: /
• Density: 1.204g/cm³
• Vapor Pressure: 8.24E-07mmHg at 25°C
• Refractive Index: 1.711
• CAS DataBase Reference: PHENYL-QUINOLIN-6-YL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYL-QUINOLIN-6-YL-AMINE(70682-98-3)
• EPA Substance Registry System: PHENYL-QUINOLIN-6-YL-AMINE(70682-98-3)

Safety Data

• Hazardous Substances Data: 70682-98-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H12N2/c1-2-6-13(7-3-1)17-14-8-9-15-12(11-14)5-4-10-16-15/h1-11,17H

Upstream product

• 580-16-5 6-hydroxyquinoline 
• 62-53-3 aniline 
• 23395-72-4 quinoline-6-carbonitrile 
• 580-15-4 6-aminoquinoline 
• 115-86-6 phosphoric acid triphenyl ester 
• 613-50-3 6-nitroquinoline 
• 98-80-6 phenylboronic acid 
• 587-65-5 N-chloroacetyl-aniline 
• 7664-93-9 sulfuric acid 
• 98-95-3 nitrobenzene 
• 56-81-5 glycerol 
• 101-54-2 N-phenylphenylene-1,4-diamine 

Relevant articles and documents

Nickel-Catalyzed Amination of Aryl Nitriles for Accessing Diarylamines through C?CN Bond Activation

A nickel-catalyzed amination to access diarylamines has been developed through C?CN bond activation of aryl nitriles with anilines. In this developed catalytic protocol, various aromatic and heteroaromatic nitriles could be utilized as the electrophiles to couple with substituted anilines. A diversity of diarylamines were obtained in 15–95% yields. (Figure presented.).

Palladium-Catalyzed C(sp2)-N Bond Cross-Coupling with Triaryl Phosphates

The first general palladium-catalyzed amination of aryl phosphates is described. The combination of MorDalPhos with [Pd(?-cinnamyl)Cl]2 enables the amination of electron-rich, electron-neutral, and electron-poor aryl phosphates with a board range of aromatic, aliphatic, and heterocyclic amines. Common functional groups such as ether, keto, ester, and nitrile show an excellent compatibility in this reaction condition. The solvent-free amination reactions are also successful in both solid coupling partners. The gram-scale cross-coupling is achieved by this catalytic system.

Br?nsted Acid Catalyzed Functionalization of Aromatic Alcohols through Nucleophilic Substitution of Hydroxyl Group

The hydroxyl groups of naphthol and tautomerizable phenol derivatives have been substituted by O-, S-, N-, and C-centered nucleophiles under solvent-free reaction conditions. The products are generated in good to excellent yields. para-Toluenesulfonic acid exhibits the best catalytic activity compared to other Bronsted acids. Experimental observations suggest that the reaction proceeds through the intermediacy of the keto tautomer of naphthol. Nucleophilic addition to the carbonyl group followed by elimination of water generates the desired product. The present methodology provides access to substituted naphtho[2,1-b]furan derivatives. The products generated using N-centered nucleophiles can be further transformed to important classes of organic molecules such as benzocarbazole and imidazole derivatives.