707-60-8

Basic information

• Product Name: 4-BROMO-N,N-DIMETHYLBENZENESULFONAMIDE
• Synonyms: p-bromo-n,n-dimethyl-benzenesulfonamid;N,N-DIMETHYL 4-BROMOBENZENESULFONAMIDE;4-BROMO-N,N-DIMETHYLBENZENESULFONAMIDE;4-BROMO-N,N-DIMETHYLBENZENESULPHONAMIDE;4-BROMOBENZENEDIMETHYLSULFONAMIDE;4-Bromo-N,N-dimethylbenzenesulphonamide 97%;4-broMo-N,N-diMethylbenzene-1-sulfonaMide;BenzenesulfonaMide, 4-broMo-N,N-diMethyl-
• CAS NO: 707-60-8
• Molecular Formula: C₈H₁₀BrNO₂S
• Molecular Weight: 264.14
• Product Categories: blocks;Bromides;Sulfonamides;Aryl;Halogenated;Organohalides;alkyl bromide
• Mol File: 707-60-8.mol
• Article Data: 20

Chemical Properties

• Melting Point: 88-90
• Boiling Point: 329 °C at 760 mmHg
• Flash Point: 152.8 °C
• Appearance: /
• Density: 1.543 g/cm³
• PKA: -5.11±0.70(Predicted)
• CAS DataBase Reference: 4-BROMO-N,N-DIMETHYLBENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-N,N-DIMETHYLBENZENESULFONAMIDE(707-60-8)
• EPA Substance Registry System: 4-BROMO-N,N-DIMETHYLBENZENESULFONAMIDE(707-60-8)

Safety Data

• Hazard Codes: Xi
• RTECS: DB0700000
• HazardClass: IRRITANT
• Hazardous Substances Data: 707-60-8(Hazardous Substances Data)

Usage

General Description

4-Bromo-N,N-dimethylbenzenesulfonamide is a chemical compound with the formula C8H10BrNO2S. It is a sulfonamide derivative used as a reagent in organic synthesis and pharmaceutical industry. The compound has a bromine substituent attached to the benzene ring, as well as two methyl groups and a sulfonamide functional group. It is commonly used as a building block in the production of various pharmaceuticals and agrochemicals. The compound has also been studied for its potential antimicrobial and anticancer activities. Overall, 4-Bromo-N,N-dimethylbenzenesulfonamide plays an important role as a versatile building block in the synthesis of various bioactive compounds.

InChI:InChI=1/C8H10BrNO2S/c1-10(2)13(11,12)8-5-3-7(9)4-6-8/h3-6H,1-2H3

Upstream product

• 108-86-1 bromobenzene 
• 124-40-3 dimethyl amine 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 106-53-6 para-bromobenzenethiol 
• 68-12-2 N,N-dimethyl-formamide 
• 1709-59-7 4-amino-N,N-dimethylbenzenesulphonamide 
• 34176-08-4 sodium 4-bromobenzenesulfinate 
• 110-18-9 N,N,N,N,-tetramethylethylenediamine 
• 87-52-5 3-(Dimethylaminomethyl)indole 
• 701-34-8 4-bromo-benzenesulfonic acid amide 
• 77-78-1 dimethyl sulfate 
• 103-83-3 N,N'-dimethylbenzylamine 

Downstream Products

• 16185-22-1 N,N-Dimethyl-4-brombenzolsulfamid 
• 486422-04-2 N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide 
• 60472-40-4 N,N-dimethyl-4-vinylbenzenesulfonamide 
• 14417-01-7 N,N-dimethylbenzenesulfonamide 
• 16185-26-5 [2-(4-Dimethylsulfamoyl-phenylsulfanyl)-phenyl]-acetic acid 
• 16185-25-4 4-(2-Cyanomethyl-phenylsulfanyl)-N,N-dimethyl-benzenesulfonamide 
• 16185-24-3 4-(2-Chloromethyl-phenylsulfanyl)-N,N-dimethyl-benzenesulfonamide 
• 16185-23-2 4-(2-Hydroxymethyl-phenylsulfanyl)-N,N-dimethyl-benzenesulfonamide 

Relevant articles and documents

A facile and versatile electro-reductive system for hydrodefunctionalization under ambient conditions

A general electrochemical system for reductive hydrodefunctionalization is described, employing the inexpensive and easily available triethylamine (Et3N) as a sacrificial reductant. This protocol is characterized by facile operation, sustainable conditions, and exceptionally wide substrate scope covering the cleavage of C-halogen, N-S, N-C, O-S, O-C, C-C and C-N bonds. Notably, the selectivity and capability of reduction can be conveniently switched by simple incorporation or removal of an alcohol as a co-solvent.

HALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF

The present invention relates to novel compounds which are capable of inhibiting certain amine oxidase enzymes. These compounds are useful for treatment of a variety of indications, e.g., fibrosis, cancer and/or angiogenesis in human subjects as well as i

Controlled synthesis of N, N-dimethylarylsulfonamide derivatives as nematicidal agents

Gramine can be intelligently and efficiently supplied with N, N-dimethylamino group and then reacted with the corresponding sulfonyl chlorides to synthesize N, N-dimethylarylsulfonamides. We herein designed and controlled synthesis of N, N-dimethylarylsulfonamide derivatives, and first reported the results of the nematicidal activity of 15 title compounds 3a-o against Meloidogyne incongnita in vitro, respectively. Among all of the title derivatives, compounds 3a, 3c, 3k, and 3o exhibited potent nematicidal activity with median lethal concentration (LC50) values ranging from 0.22 to 0.26 mg/L. Most noteworthy, N, N-dimethyl-4-methoxyphenylsulfonamide (3c) and N, N-dimethyl-8-quinolinesulfonamide (3o) showed the best promising and pronounced nematicidal activity, with LC50 values of 0.2381 and 0.2259 mg/L, respectively.