70713-45-0 Usage
Type
Synthetic chemical compound
Class
Protease inhibitor
Primary use
Treatment of HIV/AIDS
Mechanism of action
Inhibits protease enzyme activity
Function
Prevents HIV virus replication
Mode of action
Blocks enzyme to prevent virus multiplication
Combination therapy
Used with other antiretroviral drugs
Effectiveness
Reduces virus level in blood
Benefits
Improves overall health and survival of HIV/AIDS patients
Check Digit Verification of cas no
The CAS Registry Mumber 70713-45-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,7,1 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 70713-45:
(7*7)+(6*0)+(5*7)+(4*1)+(3*3)+(2*4)+(1*5)=110
110 % 10 = 0
So 70713-45-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H24N2.2ClH/c1-2-13-21-14-16-22(17-15-21)20(18-9-5-3-6-10-18)19-11-7-4-8-12-19;;/h2-12,20H,1,13-17H2;2*1H
70713-45-0Relevant articles and documents
Direct use of allylic alcohols and allylic amines in palladium-catalyzed allylic amination
Jing, Jiangyan,Huo, Xiaohong,Shen, Jiefeng,Fu, Jingke,Meng, Qinghua,Zhang, Wanbin
supporting information, p. 5151 - 5154 (2017/07/12)
Allylic alcohols and allylic amines were directly utilized in a Pd-catalyzed hydrogen-bond-activated allylic amination under mild reaction conditions in the absence of any additives. The cooperative action of a Pd-catalyst and a hydrogen-bonding solvent is most likely responsible for its high reactivity. The catalytic system is compatible with a variety of functional groups and can be used to prepare a wide range of linear allylic amines in good to excellent yields. Furthermore, this methodology can be easily applied to the one-step synthesis of two drugs, cinnarizine and naftifine, on a gram scale.
