70788-30-6

Basic information

• Product Name: 1-(2,2,6-TRIMETHYLCYCLOHEXYL)-3-HEXANOL
• Synonyms: 1-(2,2,6-TRIMETHYLCYCLOHEXYL)-3-HEXANOL;2,2,6-trimethyl-.alpha.-propyl-Cyclohexanepropanol;2,2,6-trimethyl-alpha-propyl-cyclohexanepropano;6-(2,2,6-Trimethylcyclohexyl)-4-hexanol;Timberol;Cyclohexanepropanol, 2,2,6-trimethyl-.alpha.-propyl-;2,2,6-Trimethyl-alpha-propylcyclohexanpropanol;1-(2,2,6-Trimethylcyclohexyl)hexane-3-ol
• CAS NO: 70788-30-6
• Molecular Formula: C15H30O
• Molecular Weight: 226.4
• EINECS: 274-892-7
• Mol File: 70788-30-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 280℃
• Flash Point: 124℃
• Appearance: Colourless viscous liquid
• Density: 0.850
• PKA: 15.24±0.20(Predicted)
• CAS DataBase Reference: 1-(2,2,6-TRIMETHYLCYCLOHEXYL)-3-HEXANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,2,6-TRIMETHYLCYCLOHEXYL)-3-HEXANOL(70788-30-6)
• EPA Substance Registry System: 1-(2,2,6-TRIMETHYLCYCLOHEXYL)-3-HEXANOL(70788-30-6)

Safety Data

• Hazardous Substances Data: 70788-30-6(Hazardous Substances Data)

Usage

Chemical Properties

1-(2,2,6-Trimethylcyclohexyl)- hexan-3-ol is a colorless liquid with a highly diffusive, powdery, woody odor. It is amixture of the cis- and trans-isomers. The trans-isomer has a more distinct animal and amber character. The title compound is prepared by condensation of citral with 2- pentanone in the presence of bases to give 8,12-dimethyltrideca-5,7,11-trien-4- one, which is cyclized and hydrogenated. A high-trans mixture can be prepared starting from ??-cyclocitral, which is hydrogenated to 2,2,6-trimethylcyclohexane carboxaldehyde. Condensation with 2-pentanone in the presence of sodium ethoxide yields the corresponding 3-hexenone. Hydrogenation with nickel–copper chromite as a catalyst gives a mixture with up to 95% of the trans-isomer. It is used in perfume compositions for soaps, detergents, and household products.

Trade name

Norlimbanol? (Firmenich), Timberol? (Symrise)

Upstream product

• 65562-82-5 8,12-dimethyltrideca-5,7,11-trien-4-one 
• 253454-13-6 1-(2,6,6-trimethylcyclohex-2-enyl)hex-1-en-3-ol 
• 253454-14-7 (3S)-1-(2,6,6-trimethylcyclohex-2-enyl)hex-1-en-3-ol 
• 70092-19-2 (+/-)-1-(2,6,6-trimethylcyclohex-2-enyl)hex-1-en-3-one 
• 253454-07-8 (1'S,3S,6'S)-1-(2,2,6-trimethylcyclohexyl)hex-1-en-3-ol 
• 70092-19-2 1-(2,6,6-trimethylcyclohex-2-en-1-yl)-hex-1-en-3-one 
• 70092-20-5 1-(2,6,6-trimethylcyclohex-1-en-1-yl)-hex-1-en-3-one 
• 36431-72-8 2,6,10,10-tetramethyl-1-oxaspiro[4.5]dec-6-ene 
• 7439-95-4 magnesium dihydride 
• 540-54-5 1-Chloropropane 
• 2234-82-4 1-propylmagnesium chloride 
• 107-08-4 1-iodo-propane 
• 253454-24-9 (1'S,3R,6'R)-1-(2,2,6-trimethylcyclohexyl)hexan-3-yl acetate 

Relevant articles and documents

Process for the preparation of 1-(2,2,6-trimethylcyclohexyl)-hexan-3-ol

A process for the preparation of 1-(2,2,6-trimethylcyclohexyl)-hexan-3-ol of the formula A having a content of at least 30 wt. % of the corresponding trans isomer, based on the total amount of 1-(2,2,6-trimethylcyclohexyl)-hexan-3-ol of the formula A, wit

Method for producing trimethylcyclohexyl-3-alkanols with a high portion of trans-isomers

Production of 1-(2,2,6-trimethylcyclohexyl)-3-alkanols containing trans isomers (D) comprises hydrogenating corresponding enones (B) in the presence of a nickel catalyst in the absence of copper chromite. Production of 1-(2,2,6-trimethylcyclohexyl)-3-alka

Enzyme-mediated preparation of the single enantiomers of the olfactory active components of the woody odorant Timberol

Enantiomerically pure (3S)-3a and -3b, the olfactory active forms of 1- (2,2,6-trimethylcyclohexyl)hexan-3-ol, components of the commercial woody odorant Timberol, are obtained by lipase-PS-mediated enantioselective acetylation of the allylic alcohols 6 a