71002-09-0

Basic information

• Product Name: pirazolac
• Synonyms: pirazolac;1-(4-Fluorophenyl)-4-(4-chlorophenyl)-1H-pyrazole-3-acetic acid;4-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-acetic acid;ZK-76604
• CAS NO: 71002-09-0
• Molecular Formula: C₁₇H₁₂ClFN₂O₂
• Molecular Weight: 330.74
• EINECS: 275-102-3
• Mol File: 71002-09-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 148-149°; mp 135-136°
• Boiling Point: 520.8°C at 760 mmHg
• Flash Point: 268.8°C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 1.13E-11mmHg at 25°C
• Refractive Index: 1.629
• PKA: 3.94±0.10(Predicted)
• CAS DataBase Reference: pirazolac(CAS DataBase Reference)
• NIST Chemistry Reference: pirazolac(71002-09-0)
• EPA Substance Registry System: pirazolac(71002-09-0)

Safety Data

• Hazardous Substances Data: 71002-09-0(Hazardous Substances Data)

Usage

Uses

Antirheumatic.

InChI:InChI=1/C17H12ClFN2O2/c18-12-3-1-11(2-4-12)15-10-21(20-16(15)9-17(22)23)14-7-5-13(19)6-8-14/h1-8,10H,9H2,(H,22,23)

Upstream product

• 81321-74-6 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-acetonitril 
• 77442-97-8 2-[4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione 
• 81321-66-6 3-Brommethyl-4-(4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol 
• 81321-57-5 <4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolyl>-methanol 
• 77442-96-7 <4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolyl>-methylketon 
• 81321-45-1 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester 
• 77442-95-6 1-[4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-5-morpholin-4-yl-4,5-dihydro-1H-pyrazol-3-yl]-ethanone 
• 81321-40-6 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-5-morpholino-4,5-dihydro-pyrazol-3-carbonsaeure-ethylester 
• 81321-33-7 (E)-N-[2-(4-Chlorophenyl)ethenyl]morpholine 
• 140-53-4 p-chlorobenzyl cyanide 

Downstream Products

• 90934-29-5 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-essigsaeure(11β,17-dihydroxy-3,20-dioxo-4-pregnen-21-yl)-ester 
• 87267-69-4 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-acetoxyessigsaeure-tert.butylester 
• 87267-79-6 2-<4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolyl>-ethanol 
• 87267-68-3 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-essigsaeurechlorid 
• 86768-16-3 5-Chlor-4-(4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-essigsaeure 
• 87267-82-1 <4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolyl>-acetamid 
• 87267-84-3 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-acetohydroxamsaeure 
• 87267-83-2 N-<4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolylacetyl>-glycin 
• 87267-85-4 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-acetoxyessigsaeure 
• 87267-80-9 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-essigsaeure-(2-dimethylaminoethyl)-ester 
• 87267-81-0 4-<4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolylacetyl>-morpholin 
• 87267-78-5 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-essigsaeure-ethylester 

Relevant articles and documents

Leukotriene biosynthesis inhibitors

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Process for the preparation of (1,4-diaryl-pyrazol-3-yl)-acetic acids

(1,4-diaryl-pyrazol-3-yl)-acetic acids of the formula I wherein Ar and Ar?, which can be the same or differen, represen a phenyl group optionally substituted with 1 to 3 halogen atoms, C1-C4 alkyl or C1-C4 alkoxy groups, are prepared by reacting β-styryl amines with compounds of formula ClCO-CH2-A (wherein A represent a CN, COOR or CONR1R2 group, R being an alkyl, benzyl or benzohydryl group and R1and R2 being H or an alkyl, benzyl or benzohydryl group).