714194-68-0 Usage
Description
Octahydro-cyclopenta[c]pyrrole-1-carboxylic acid tert-butyl ester is a cyclopentane-based chemical compound, specifically an ester derivative of cyclopenta[c]pyrrole-1-carboxylic acid, featuring a tert-butyl group attached to its carboxylic acid moiety. This versatile molecule is recognized for its utility in organic synthesis and potential biological activities, positioning it as a significant player in medicinal and agricultural chemistry.
Uses
Used in Organic Synthesis:
Octahydro-cyclopenta[c]pyrrole-1-carboxylic acid tert-butyl ester serves as a valuable building block in the preparation of an array of pharmaceuticals and agrochemicals. Its structural attributes make it a key component in the development of new molecules with therapeutic and pesticidal properties.
Used in Pharmaceutical Industry:
Within the pharmaceutical sector, Octahydro-cyclopenta[c]pyrrole-1-carboxylic acid tert-butyl ester is utilized as a precursor for the synthesis of drugs with potential anti-inflammatory and analgesic effects. Its capacity to modulate biological responses positions it as a candidate for the treatment of various inflammatory conditions and pain management.
Used in Agrochemical Industry:
Similarly, in agrochemical applications, Octahydro-cyclopenta[c]pyrrole-1-carboxylic acid tert-butyl ester is employed in the creation of compounds designed to protect crops from pests and diseases, leveraging its reactivity and structural features to enhance agricultural productivity.
Check Digit Verification of cas no
The CAS Registry Mumber 714194-68-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,1,4,1,9 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 714194-68:
(8*7)+(7*1)+(6*4)+(5*1)+(4*9)+(3*4)+(2*6)+(1*8)=160
160 % 10 = 0
So 714194-68-0 is a valid CAS Registry Number.
714194-68-0Relevant articles and documents
Stereoselective lithiation and carboxylation of Boc-protected bicyclopyrrolidine: Synthesis of a key building block for HCV protease inhibitor telaprevir
Tanoury, Gerald J.,Chen, Minzhang,Dong, Yong,Forslund, Raymond,Jurkauskas, Valdas,Jones, Andrew D.,Belmont, Daniel
, p. 1234 - 1244 (2014/12/10)
A stereoselective process for the manufacture of bicyclopyrrolidine 7 to 2 has been developed. The process utilizes a stereoselective lithiation/carboxylation sequence. The achiral diamine ligand DPBP induces excellent diastereocontrol, and resolution with (S)-THNA provides the corresponding salt of 8 in high er and dr. Subsequent processing of 8 gives 2 as the oxalate salt in an overall yield of 27% from 7 (based on total molar charge of 7). Compound 2 was obtained with high chemical and chiral purities. The process was successfully demonstrated on >100 kg scale.
PROCESS FOR THE PREPARATION OF PROTEASE INHIBITORS
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Page/Page column 36, (2012/12/13)
A process for preparing enantioselectively a compound of formula (la) or (Ib) over a compound of formulas I-2—1h.
Processes and intermediates
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Page/Page column 44; 45, (2010/11/26)
The invention relates to compounds and processes useful for the preparation of protease inhibitors, particularly serine protease inhibitors. The protease inhibitors are useful for treatment of HCV infections.
