7153-22-2

Basic information

• Product Name: Ethyl 4-cyanobenzoate
• Synonyms: Benzoic acid, 4-cyano-, ethyl ester;P-CYANOBENZOIC ACID ETHYL ESTER;RARECHEM AL BI 0074;ETHYL 4-CYANOBENZOATE;4-CYANOBENZOIC ACID ETHYL ESTER;ethyl cyanobenzoate;Ethyl 4-cyanobenzoate,99%;Ethyl 4-cyanobenzoate 99%
• CAS NO: 7153-22-2
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18
• EINECS: 230-500-6
• Product Categories: FINE Chemical & INTERMEDIATES;Aromatic Esters;C10 to C11;Carbonyl Compounds;Esters;Building Blocks;C10 to C11;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 7153-22-2.mol
• Article Data: 76

Chemical Properties

• Melting Point: 52-54 °C(lit.)
• Boiling Point: 140°C/11mmHg(lit.)
• Flash Point: >230 °F
• Appearance: white to light yellow crystalline powder
• Density: 1.1999 (rough estimate)
• Vapor Pressure: 0.00112mmHg at 25°C
• Refractive Index: 1.5060 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: Ethyl 4-cyanobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 4-cyanobenzoate(7153-22-2)
• EPA Substance Registry System: Ethyl 4-cyanobenzoate(7153-22-2)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36-36/37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 7153-22-2(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystalline powder

InChI:InChI=1/C10H9NO2/c1-2-13-10(12)9-5-3-8(7-11)4-6-9/h3-6H,2H2,1H3

Upstream product

• 16331-64-9 ethanolate 
• 32792-60-2 4-nitrophenyl 4-cyanobenzoate 
• 141-78-6 ethyl acetate 
• 104-85-8 para-methylbenzonitrile 
• 623-00-7 4-bromobenzenecarbonitrile 
• 1906-57-6 potassium monoethyl oxalate 
• 64-17-5 ethanol 
• 105-07-7 4-cyanobenzaldehyde 
• 6068-72-0 4-cyanobenzoyl chlorIde 
• 15226-74-1 dicobalt octacarbonyl 
• 66107-32-2 4-cyanophenyl trifluoromethanesulfonate 
• 557-21-1 zinc(II) cyanide 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 21864-90-4 N-(tert-butyl)benzimidoyl cyanide 

Downstream Products

• 116655-43-7 4-((Z)-1-Hydroxy-2-pyrazin-2-yl-vinyl)-benzonitrile 
• 62585-03-9 1-(4-cyanophenyl)-1,3-butanedione 
• 1226772-06-0 2-(3-chlorobenzoyl)-4-cyanobenzoic acid ethyl ester 
• 1258944-79-4 p-EtOOC(C₆H₄)CH=N(SiMe₂Ph) 
• 1268691-75-3 2-(4-ethoxycarbonylphenyl)-1H-indole-3-carboxylic acid ethyl ester 
• 623-26-7 terephthalonitrile 
• 64-17-5 ethanol 
• 874-89-5 4-Cyanobenzyl alcohol 
• 101890-75-9 4-(6,7-dimethoxy-4H-benzo[e][1,3]thiazin-2-yl)-benzoic acid ethyl ester 
• 5418-97-3 4-amidino-benzoic acid ethyl ester hydrochloride 
• 97582-63-3 4-(2-amino [1,2,4]triazolo[1,5-c]pyrimidin-5-yl)benzoic acid, ethyl ester 
• 97603-46-8 4-(4-Hydrazino-pyrimidin-2-yl)-benzoic acid ethyl ester 
• 97582-70-2 5-(3-chlorophenyl)[1,2,4]triazolo[1,5-c]pyrimidin-2-amine 
• 97604-14-3 4-(4-chloropyrimidin-2-yl)benzic acid ethyl ester 

Relevant articles and documents

Production of Copolyester Monomers from Plant-Based Acrylate and Acetaldehyde

PCTA is an important copolyester that has been widely used in our daily necessities. Currently, its monomers are industrially produced from petroleum-derived xylene. To reduce the reliance on fossil energy, we herein disclose an alternative route to acces

Vitamin B1-catalyzed aerobic oxidative esterification of aromatic aldehydes with alcohols

A straightforward aerobic oxidative esterification of aryl aldehydes with alcohols has been developed for the synthesis of substituted esters by employing vitamin B1 as a cost-effective, metal-free, and eco-friendly NHC catalyst. Air is used as a green terminal oxidant. The reaction is a useful addition to the existing NHC-catalytic oxidative esterification.

Zn-catalyzed cyanation of aryl iodides

We report the first example of zinc-catalyzed cyanation of aryl iodides with formamide as the cyanogen source. The transformation was promoted by the bisphosphine Nixantphos ligand. Under optimized conditions, a variety of electron-donating and electron-withdrawing aryl iodides were converted into nitrile products in good to excellent yields. This approach is an exceedingly simple and benign method for the synthesis of aryl nitriles and is likely to proceed via a dinuclear Zn-concerted catalysis.