71556-64-4Relevant articles and documents
Synthesis of 2-phenyl- and 2,2-diarylpyrrolidines through Stevens rearrangement performed on azetidinium ions
Drouillat, Bruno,D'Aboville, Edouard,Bourdreux, Flavien,Couty, Francois
supporting information, p. 1103 - 1109 (2014/03/21)
A set of azetidinium ions substituted at the nitrogen atom either by a benzyl group or a benzhydryl group were synthesized to delineate the scope of their ring expansion into 2-phenyl- or 2,2-diaryl-pyrrolidines through a Stevens rearrangement. Whereas th
Synthesis and structure-activity relationships of aminoalkylazetidines as ORL1 receptor ligands
Wu, Wen-Lian,Caplen, Mary Ann,Domalski, Martin S.,Zhang, Hongtao,Fawzi, Ahmad,Burnett, Duane A.
, p. 3157 - 3160 (2007/10/03)
A series of aminoalkylazetidines has been discovered as novel ORL1 receptor ligands. Structure-activity relationships have been investigated at the azetidine N and the alkyl side chain sites. Several potent and selective analogues have been identified.