7160-22-7

Basic information

• Product Name: 3',4'-DICHLOROPIVALANILIDE
• Synonyms: TIMTEC-BB SBB008104;3',4'-DICHLOROPIVALANILIDE;AURORA 5475;N-(3,4-Dichlorophenyl)-2,2-dimethylpropanamide;2,2-Dimethyl-N-(3,4-dichlorophenyl)propanamide;N-(3,4-Dichlorophenyl)pivalaMide;N-(3,4-dichlorophenyl)2,2-dimethyl-propionamide;Propanamide, N-(3,4-dichlorophenyl)-2,2-dimethyl-
• CAS NO: 7160-22-7
• Molecular Formula: C₁₁H₁₃Cl₂NO
• Molecular Weight: 246.13
• Mol File: 7160-22-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 377.1 °C at 760 mmHg
• Flash Point: 181.9 °C
• Appearance: /
• Density: 1.255 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3',4'-DICHLOROPIVALANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3',4'-DICHLOROPIVALANILIDE(7160-22-7)
• EPA Substance Registry System: 3',4'-DICHLOROPIVALANILIDE(7160-22-7)

Safety Data

• Hazardous Substances Data: 7160-22-7(Hazardous Substances Data)

Usage

General Description

3',4'-dichloropivalanilide is a chemical compound with the molecular formula C11H13Cl2NO. It is a derivative of pivalanilide, and its structure consists of a pivaloyl group attached to a 3',4'-dichloroaniline moiety. 3',4'-DICHLOROPIVALANILIDE is often used as a building block in organic synthesis and as a precursor for the preparation of other chemicals. It has also been investigated for its potential biological activity, such as its use as an insecticide and herbicide. 3',4'-dichloropivalanilide is a white to off-white solid that is sparingly soluble in water but soluble in organic solvents. Its chemical properties and structure make it a valuable tool in the field of organic and medicinal chemistry.

Upstream product

• 3282-30-2 pivaloyl chloride 
• 95-76-1 m,p-dichloroaniline 

Relevant articles and documents

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A compound as a CXCR2 antagonist and an application thereof in preparing a drug as a CXCR2 antagonist. In particular, the present invention relates to a compound represented by formula (II) or an isomer or pharmaceutically acceptable salt thereof.

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Here, we report a dual catalytic approach for room temperature direct arylation of C-H bonds with aryldiazonium salts as a simple aryl group donor, also working as an internal oxidant via C-N2 bond cleavage. This unified strategy has been achieved by the synergistic combination of visible-light metal-free photoredox and palladium catalysis under silver-, base- and/or additive-free conditions. The broad substrate scope, functional group tolerance, excellent regioselectivity and redox-neutral conditions of this process make it attractive for the effective synthesis of a wide range of important N-heterocyclic commodities such as dibenzo[b,d]azepine, carbazole and phenanthridine.

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