72090-82-5

Basic information

• Product Name: IMidazo[1,2-b]pyridazine-3-carbonitrile
• Synonyms: IMidazo[1,2-b]pyridazine-3-carbonitrile
• CAS NO: 72090-82-5
• Molecular Formula: C7H4N4
• Molecular Weight: 144.13346
• Mol File: 72090-82-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: IMidazo[1,2-b]pyridazine-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: IMidazo[1,2-b]pyridazine-3-carbonitrile(72090-82-5)
• EPA Substance Registry System: IMidazo[1,2-b]pyridazine-3-carbonitrile(72090-82-5)

Safety Data

• Hazardous Substances Data: 72090-82-5(Hazardous Substances Data)

Upstream product

• 590-17-0 cyanomethyl bromide 
• 35053-54-4 N,N-dimethyl-N'-pyridazin-3-yl-formamidine 

Relevant articles and documents

Synthesis method of imidazo[1, 2-b]pyridazine-3-carbonitrile

The invention relates to a synthesis method of imidazo[1, 2-b]pyridazine-3-carbonitrile. The method includes: taking 3-aminopyridazine, DMF-DMA and bromoacetonitrile as the raw material, with the amount of 3-aminopyridazine and the amount of DMF-DMA being in a ratio of 1:0.9-3.1, and the amount of 3-aminopyridazine and the amount of bromoacetonitrile being in a ratio of 1:1.0-3.5, in an appropriate solvent and under the action of alkali, carrying out continuous reaction at 45-170DEG C to generate imidazo[1, 2-b]pyridazine-3-carbonitrile crude product, and performing purification to obtain an imidazo[1, 2-b]pyridazine-3-carbonitrile pure product. According to the invention, the raw materials are easily available and reasonable in price, also heavy metal and corrosive gas are not involved in the preparation reaction, the reaction is mild and has no special requirement for the reaction equipment, and common corrosion resistant equipment can realize production. In addition, the reaction conditions of the method involved in the invention are moderate.