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72130-68-8

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72130-68-8 Usage

General Description

Ethyl 7-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate is a synthetic compound with a complex chemical structure. It is an ester, derived from the indolizine ring system and containing a hydroxy group on the 7th carbon, a carbonyl group on the 5th carbon, and an ethyl ester group on the 8th carbon. Ethyl 7-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate is not naturally occurring and is primarily used in research and pharmaceutical development. Its specific properties and potential applications may vary, but it is likely to have biological or pharmacological activity due to its unique structure and functional groups. Further studies and testing are necessary to fully understand the potential uses and effects of Ethyl 7-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate.

Check Digit Verification of cas no

The CAS Registry Mumber 72130-68-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,1,3 and 0 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 72130-68:
(7*7)+(6*2)+(5*1)+(4*3)+(3*0)+(2*6)+(1*8)=98
98 % 10 = 8
So 72130-68-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO4/c1-2-16-11(15)10-7-4-3-5-12(7)9(14)6-8(10)13/h6,13H,2-5H2,1H3

72130-68-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 7-hydroxy-5-oxo-2,3-dihydro-1H-indolizine-8-carboxylate

1.2 Other means of identification

Product number -
Other names ethyl 7-hydroxy-5-oxo-1,2,3,5-tetrahydro-8-indolizinecarboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:72130-68-8 SDS

72130-68-8Relevant articles and documents

Propionic Acid Derivatives and Methods of Use Thereof

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Paragraph 1811; 1813, (2018/11/21)

Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5 and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomers of these compounds. In addition methods are provided for inhibiting the binding of an integrin to treat various pathophysiological conditions.

Heterocyclic Compounds as MEK Inhibitors

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Page/Page column 18, (2009/12/02)

The present invention relates to compounds of formula I and pharmaceutically acceptable salts. These compounds can act as potential MEK inhibitors in the treatment of hyperproliferative diseases, like cancer and inflammation. The present invention also reveals methods of preparation thereof.

Annulation of heterocyclic secondary enamines with dicarboxylic acid dichlorides, an unexpected ring size effect

Cheng, Ying,Yang, Hai-Bo,Huang, Zhi-Tang,Wang, Mei-Xiang

, p. 1757 - 1759 (2007/10/03)

Under very mild conditions heterocyclic secondary enamines react efficiently with malonyl chloride to produce hydroxylated 2-pyridinone-fused heterocycles. The reactions of enamines with oxalyl chloride, however, afford varied products depending upon the heterocyclic structure of the enamine. Whilst a C-acylated enamine and a lactam-fused heterocycle were obtained from the reaction of the five- and seven-membered heterocyclic enamines, respectively, the six-membered heterocyclic enamine gave 2-oxo-5,6,7,8-tetrahydro-2H-pyrido[3,2-b]pyran. The reaction mechanisms are discussed.

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