721402-02-4

Basic information

• Product Name: 4-BROMO-1,5-DIMETHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE
• Synonyms: 4-BROMO-1,5-DIMETHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE;1H-pyrazole, 4-bromo-1,5-dimethyl-3-(trifluoromethyl)-;4-bromo-1,5-dimethyl-3-(trifluoromethyl)-1H-pyrazole(SALTDATA: FREE);4-bromo-1,5-dimethyl-3-(trifluoromethyl)pyrazole;4-Bromo-1,5-dimethyl-3-(trifluoromethyl)-1H-pyrazole98%
• CAS NO: 721402-02-4
• Molecular Formula: C6H6BrF3N2
• Molecular Weight: 243.02
• Product Categories: Pyrazoles & Triazoles;Halides;Pyrazoles & Triazoles;Building Blocks;Pyrazole
• Mol File: 721402-02-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 210.285°C at 760 mmHg
• Flash Point: 80.978°C
• Appearance: /
• Density: 1.724g/cm³
• Vapor Pressure: 0.281mmHg at 25°C
• Refractive Index: 1.507
• CAS DataBase Reference: 4-BROMO-1,5-DIMETHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-1,5-DIMETHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE(721402-02-4)
• EPA Substance Registry System: 4-BROMO-1,5-DIMETHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE(721402-02-4)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45
• HazardClass: IRRITANT
• Hazardous Substances Data: 721402-02-4(Hazardous Substances Data)

Usage

General Description

4-Bromo-1,5-dimethyl-3-(trifluoromethyl)-1H-pyrazole is a chemical compound with the molecular formula C7H7BrF3N2. It is a pyrazole derivative that contains a bromine atom and a trifluoromethyl group. 4-BROMO-1,5-DIMETHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE is often used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Its structure and properties make it a versatile intermediate in organic synthesis, and it is commonly used for the functionalization of various aromatic compounds. The bromine and trifluoromethyl groups in 4-bromo-1,5-dimethyl-3-(trifluoromethyl)-1H-pyrazole make it a valuable reagent for the introduction of these functional groups into organic molecules, making it an important compound in the field of synthetic chemistry.

InChI:InChI=1/C6H6BrF3N2/c1-3-4(7)5(6(8,9)10)11-12(3)2/h1-2H3

Upstream product

• 79080-31-2 1,5-dimethyl-3-(trifluoromethyl)pyrazole 
• 367-57-7 1,1,1-Trifluoro-2,4-pentanedione 
• 10010-93-2 5-methyl-3-trifluoromethyl-1H-pyrazole 
• 60061-68-9 4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazole 
• 74-88-4 methyl iodide 

Downstream Products

• 1082065-80-2 1,5-dimethyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde 

Relevant articles and documents

COMPOUNDS AND THEIR USE AS INHIBITORS OF N-MYRISTOYL TRANSFERASE

This invention provides compounds of formula (I) and salts thereof, which have activity as inhibitors of N-myristoyl transferase (NMT). The invention also relates to uses of such compounds as medicaments, in particular in the treatment of a disease or disorder in which inhibition of N-myristoyl transferase provides a therapeutic or prophylactic effect, including protozoan infections (such as malaria and leishmaniasis), viral infections (such as human rhinovirus and HIV), and hyperproliferative disorders (such as B-cell lymphoma).

2-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-3-PHENYL PYRAZINES AND PYRIDINES AND 3-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-2-PHENYL PYRIDINES AS 5-HT7 RECEPTOR ANTAGONISTS

The present invention provides selective 5-HT7 receptor antagonist compounds of Formula I and their use in the treatment of migraine, persistent pain, and anxiety: where A and B are each independently C(H)= or N=, provided that at least one of A and B is -N=, n is 1-3, m is 0-3, and R14 are as defined herein.

Pyrazolylarylalkines

The present invention relates to pyrazolylarylalkines and to their use, to a process for preparing pyrazolylarylalkines and also to intermediates.