72141-41-4

Basic information

• Product Name: (4-NITRO-PHENYL)-PIPERAZIN-1-YL-METHANONE
• Synonyms: AKOS BB-6408;(4-NITRO-PHENYL)-PIPERAZIN-1-YL-METHANONE;(4-NITROPHENYL)(PIPERAZINO)METHANONE;1-(4-NITROBENZOYL)-PIPERAZINE;BUTTPARK 153\33-43
• CAS NO: 72141-41-4
• Molecular Formula: C₁₁H₁₃N₃O₃
• Molecular Weight: 235.24
• Product Categories: piperazines
• Mol File: 72141-41-4.mol
• Article Data: 28

Chemical Properties

• Melting Point: 158-161°C
• Boiling Point: 443.9°C at 760 mmHg
• Flash Point: 222.2°C
• Appearance: /
• Density: 1.289g/cm³
• Vapor Pressure: 4.48E-08mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: 2-8°C(protect from light)
• PKA: 8.24±0.10(Predicted)
• CAS DataBase Reference: (4-NITRO-PHENYL)-PIPERAZIN-1-YL-METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-NITRO-PHENYL)-PIPERAZIN-1-YL-METHANONE(72141-41-4)
• EPA Substance Registry System: (4-NITRO-PHENYL)-PIPERAZIN-1-YL-METHANONE(72141-41-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 72141-41-4(Hazardous Substances Data)

Usage

General Description

"(4-Nitro-Phenyl)-Piperazin-1-yl-Methanone" is a chemical compound notable for its unique structure. This organic compound is characterized by a central methanone group bonded to a piperazine ring, with a nitrophenyl group positioned at the 4th carbon of the ring. The presence of the nitro group and piperazine suggests that it can potentially be used in the synthesis of various pharmaceutical drugs. However, specific information about its physical properties, toxicity, and applications is not widely available, indicating that it is likely primarily used in research settings and is not commonly found in everyday products or applications.

InChI:InChI=1/C11H13N3O3/c15-11(13-7-5-12-6-8-13)9-1-3-10(4-2-9)14(16)17/h1-4,12H,5-8H2

Upstream product

• 110-85-0 piperazine 
• 62-23-7 4-nitro-benzoic acid 
• 5366-37-0 4-nitrobenzoic acid 2-pyridinyl ester 
• 636-98-6 p-nitrobenzene iodide 
• 13939-06-5 molybdenum hexacarbonyl 
• 509073-62-5 tert-butyl 4-(4-nitrobenzoyl)piperazine- 1-carboxylate 
• 10364-96-2 N-(4-nitrobenzoyl)imidazole 
• 142-64-3 piperazine dihydrochloride 
• 122-04-3 4-nitro-benzoyl chloride 
• 22044-09-3 piperazinium 
• 35612-14-7 S-2,4-dinitrophenyl 4-nitrothiobenzoate 
• 69737-96-8 S-(p-nitrophenyl) p-nitrothiobenzoate 
• 78823-40-2 pivalic p-nitrobenzoic anhydride 
• 1037-31-6 4-nitrophenyl 4-nitrobenzoate 

Downstream Products

• 1622867-09-7 C₂₅H₂₁N₅O₅S 
• 462616-51-9 C₁₄H₁₉N₃O₃ 
• 892495-32-8 2-[4-(4-nitrobenzoyl)-1-piperazinomethyl]-3,5,6-trimethylpyrazine 
• 1075248-10-0 C₂₁H₁₇N₃O₆ 

Relevant articles and documents

Solar and visible-light active nano Ni/g-C3N4photocatalyst for carbon monoxide (CO) and ligand-free carbonylation reactions

In this study, we investigate the amino and alkoxycarbonylation reaction between various substituted aryl halides, benzyl iodides, and iodocyclohexane with different types of amines and alcohols in the absence of carbon monoxide gas and ligands. Similar reactions are carried out at high temperatures, in the presence of appropriate ligands, stoichiometric amounts of bases, and gaseous carbon monoxide, which endanger the health of organic chemists. We present a novel method that does not utilize ligands, bases, gaseous CO, and special conditions. This procedure is a redox reaction carried out by new economic nano Ni/g-C3N4at room temperature and under visible light. Mo(CO)6was used toin situgenerate CO, to resolve the problems caused by the use of CO gas. This protocol has the ability to be used on a gram scale by using a continuous flow reactor.

NMR-based investigations of acyl-functionalized piperazines concerning their conformational behavior in solution

Selected N-benzoylated piperazine compounds were synthesized to study their conformational behavior using temperature-dependent 1H NMR spectroscopy. All investigated piperazines occur as conformers at room temperature resulting from the restric

Substituted O-hydroxyphenyl ketone compound as well as preparation method and application thereof

The invention discloses a substituted O-hydroxyphenyl ketone compound, a preparation method of the substituted O-hydroxyphenyl ketone compound, and an application of the substituted O-hydroxyphenyl ketone compound to preparation of a BRD4 protein activity